This book is a fact-based guide to the appropriate use of fish oil as nature's safest and most effective anti-inflammatory.

Chronic pain seldom presents alone. Pain patients frequently have comorbid psychiatric conditions and those suffering from mental illness often experience pain. Nonetheless, pain conditions and psychiatric disorders have customarily been understood and treated as different and separate clinical entities, to the detriment of patients' wellbeing. This book will describe the complex and striking relationships between pain and psychiatric disorders, offering the first comprehensive review of the challenging and neglected intersection between pain medicine and psychiatry. Written by world-renowned experts in the fields of pain and psychiatry, chapters contribute a valuable array of clinical and theoretical perspectives and include illustrative case examples throughout.

Recognized experts comprehensively review the clinical, surgical, radiological, and scientific aspects of atherosclerotic peripheral arterial disease (PAD), including endovascular, gene, and drug therapies. In their far-ranging discussions, the authors examine in depth the risk factors and antiplatelet therapies for PAD patients at high risk for suffering a heart attack and/or and stroke, the question of exercise rehabilitation, the surgical approaches to revascularization, and the preoperative evaluation and perioperative management of the vascular patient. Completing this detailed overview is important information on ameliorating the risk factors for PAD, its pathogenesis and epidemiology, and the physiological and pathophysiological basis of available diagnostic tests.

Whilst the body has recently assumed greater sociological significance, there has been less engagement in social work and social care on the bodily experience of health, illness and disease. This innovative volume redresses the balance by exploring chronic illness and social work, through the specific lens of autoimmunity, engaging in wider debates around vulnerability, resistance and the lived experience of ongoing ill-health. Moving beyond existing conceptualisations of vulnerability as an issue of mental distress, ageing, child protection and poverty, Price and Walker demonstrate the role that society has to play in actively engaging the physical body, rather than working around and through it. The book focuses on auto-immune conditions such as lupus, multiple sclerosis, rheumatoid arthritis and scleroderma. Conditions like these allow for an exploration of the materiality of illness which exacerbates social and economic vulnerability and may precipitate personal and social crises, requiring a variety of interventions and support. The risks and challenges associated with chronic illness include disruptions to a sense of self and identity, altered relationships and the renegotiation of roles and responsibilities in a variety of relationships in addition to an economic impact, with the potential for disruption to employment status and financial insecurity. This text opens up a range of debates around some of the central concerns of the social work profession, including vulnerability, ill-health, and independence. It will be of interest to scholars and students of social work, nursing, disability studies, medicine and the social sciences.

The monograph applies sophisticated topological symmetry tools to biological applications of information theory, along with a Black-Scholes model invocation of the Data Rate Theorem which links information and control theories. The focus is on statistical mechanics and other models that explore pathological phase transitions - driven by changes in available rates of mitochondrial free energy - in physiological functions, a cutting-edge topic in the study of chronic disease. One of the key focuses is Alzheimer's disease - a relatively simple canonical example.

Gene therapy for inflammatory diseases is a new, burgeoning field of medicine. Edited by the undisputed pioneers of this area of research, this volume is the first devoted to its topic. It contains thirteen chapters, each written by leaders in their respective fields, that summarize the state of the art in developing novel, gene based treatments for inflammatory diseases. As well as providing an introduction to the basic concepts of gene therapy and the use of naked DNA approaches, the book describes the advances that have been made in applying them to arthritis, lupus, multiple sclerosis, diabetes, Sjogrens syndrome and transplantation.One chapter is devoted to discussing the first human clinical trials that apply gene therapy to the treatment of an inflammatory disease. As well as providing novel therapeutic approaches, gene therapy facilitates the development of new and improved animal models of disease; a chapter describing these advances is also included. As an up-to-date, timely book written by th

This book is concerned with driver fatigue across all transport modes. Most research into the effects of fatigue has been restricted to studies of road users but with new estimates showing more crashes can be attributed to fatigue than previously thought, fatigue is increasingly being seen as a significant public health problem. Drawing together research into fatigue and its management in all transport modes, this book shows that much can be learned from approaching the phenomenon in an integrative way. Exposing common misconceptions and exploring key research findings, the book presents the true complexity of the problem by bringing together up-to-date review contributions from experts on the causes and countermeasures to fatigues. The work will give policy makers a sound basis for formulating changes in regulatory frameworks as well as providing the research community and the concerned public with a complete picture of this complex problem and its solutions.

The information in Healthy Solutions can help readers maintain and enhance their own health. Readers will come to understand how natural medicine views health, disease, and healing. Also, how to interpret the body's reaction to illness, and become familiar with self-care remedies for more than 50 health conditions. Explains how to use homopathic tissue salts for treating symptoms, and how to master the therapeutic uses of herbs, spices, and foods.

Encyclopedic in scope, Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 3: Environmental Manifestations of the Neurocardiovascular Systems draws deeply from clinical histories of thousands of patients. It focuses on clinical syndromes within the musculoskeletal, neurological, and cardiovascular systems with a special focus on vascular dysfunction and heart failure treatment. The book explores mechanisms of chemical sensitivity and chronic degenerative disease, their manifestations, diagnosis, and approaches to reverse dysfunction. It covers a wide variety of topics including environmental sensitivity due to external pollutants, environmental control for reducing total body load, pollutant damage to vascular perfusion, altered blood volume, fluctuations of oxygen extraction, effects of endocrine on the vascular system, effects of pollutants on myocardial cells, and mechanisms in vascular damage. The book also discusses in detail a wide variety of clinical manifestations including vasculitis, cardiac arrhythmias, cardiac metabolic syndrome, myocarditis, atherosclerosis, heart failure, urticaria, and anaphylaxis. Treatment for heart failure is also discussed. The third volume of a five-volume set, the book provides an essential resource for health care providers diagnosing and treating chemical sensitivity and chronic degenerative disease.

There are common midlife events that account for the special narcissistic vulnerabilities of this period of life, and Eda Goldstein ably reviews these events and the theoretical perspectives commonly brought to bear on them. In When the Bubble Bursts, however, Goldstein's special concern is those individuals who come to midlife with heightened narcissistic vulnerabilities that make the navigation of this stage of life more difficult still. In understanding the latter such patients and devising a treatment approach appropriate to their "self" issues, Goldstein adopts a broadly self-psychological frame of reference. It is a matter, she finds again and again, of understanding how current stressors frustrate healthy self needs and trigger narcissistic vulnerabilities. Self-psychologically informed treatment, which, in Goldstein's pragmatic purview, embraces modalities that are, to varying degrees, supportive, psychodynamic, and psychoanalytic, reworks and strengthens self structures in helping patients find new ways of affirming their sense of self. Her substantive case studies, which accompany the reader through all the chapters in her study, draw on personal and supervisory experiences to illustrate crucial foci of the treatment process with a range of midlife patients in psychotherapy. Eda Goldstein presents a study that comprises an admirable blend of theoretical astuteness, clinical wisdom, and personal honesty. Her clinical study of midlife narcissistic pathology is bracketed by her balanced discussion of theoretical perspectives on adult development and her concluding consideration of the countertransference issues elicited by midlife patients in midlife therapists. When the Bubble Bursts is an edifying contribution to the literatures of psychodynamic psychotherapy, self psychology, and adult development.

Liver disease is the leading cause of death after heart, cancer, stroke and respiratory disease, and kills more people than diabetes and road deaths combined. But, there is hope. The liver is a uniquely regenerative organ, and some European countries have dramatically cut liver disease in recent years. This book looks at lifestyle factors and medical interventions that can help.

There are 7,000 rare diseases affecting 6%-8% of the global population. That's 3.5 million people in the UK alone. Yet only 200 rare diseases have approved treatments. In recent years, there has been a surge of interest from business and social entrepreneurs in the field of health - including looking at ways to treat rare disease patients better and faster. This book presents some of the latest developments in the world of rare disease entrepreneurship from a global group of experts. It examines the topic from the business angle, considering the drug development process and providing case studies of successful orphan drug enterprises. It also looks at rare diseases from the perspective of the patient, analysing the growing rare disease patient movement, a successful patient group that uses social enterprise techniques, and chapters on key requirements for helping patients with rare diseases through registries and centres of excellence. The book will be an essential toolkit for social and business entrepreneurs who are interested in the world of rare/orphan diseases. It has the rigour of an academic publication, along with the clarity of a lay publication. An original and timely book, Rare Diseases will help to add knowledge and awareness to a vastly under-published subject.

Patients suffering from psychosomatic disorders represent a formidable challenge. Psychosomatic disorders are common, and account for substantial personal discomfort, unnecessary medical expenditures, socioeconomic loss, and disability. They are challenging to diagnose, treat, and are rarely completely cured. Furthermore, they often provoke strong negative reactions from family, friends, and caregivers, who are unable to fathom their inconsistencies. Currently, little is known as to how they develop or why their symptoms tend to transform over time. In Pathologies of the Mind/Body Interface, Richard Kradin, a medical internist, pulmonologist, and psychoanalyst at a large Harvard hospital, examines the historical, philosophical, cultural, psychological, and neurobiological factors that contribute to the development of psychosomatic disorders. He focuses on the role that developmental stress and attachment disorders appear to play in increasing the risk of developing psychosomatic symptoms, and advises medical practitioners and psychologists on how to diagnose and treat them. Dr. Kradin suggests areas of importance for future medical and psychological research into the causes and treatments of these debilitating disorders.

Patients suffering from psychosomatic disorders represent a formidable challenge. Psychosomatic disorders are common, and account for substantial personal discomfort, unnecessary medical expenditures, socioeconomic loss, and disability. They are challenging to diagnose, treat, and are rarely completely cured. Furthermore, they often provoke strong negative reactions from family, friends, and caregivers, who are unable to fathom their inconsistencies. Currently, little is known as to how they develop or why their symptoms tend to transform over time. In Pathologies of the Mind/Body Interface, Richard Kradin, a medical internist, pulmonologist, and psychoanalyst at a large Harvard hospital, examines the historical, philosophical, cultural, psychological, and neurobiological factors that contribute to the development of psychosomatic disorders. He focuses on the role that developmental stress and attachment disorders appear to play in increasing the risk of developing psychosomatic symptoms, and advises medical practitioners and psychologists on how to diagnose and treat them. Dr. Kradin suggests areas of importance for future medical and psychological research into the causes and treatments of these debilitating disorders.

If the word "cure" intrigues you, this book will also. High doses of vitamins have been known to cure serious illnesses for nearly 80 years.

Claus Jungeblut, M.D., prevented and treated polio in the mid-1930s, using a vitamin. Chest specialist Frederick Klenner, M.D., was curing multiple sclerosis and polio back in the 1940s, also using vitamins. William Kaufman, M.D., cured arthritis, also in the 1940s. In the 1950s, Drs. Wilfrid and Evan Shute were curing various forms of cardiovascular disease with a vitamin. At the same time, psychiatrist Abram Hoffer was using niacin to cure schizophrenia, psychosis, and depression. In the 1960s, Robert Cathcart, M.D., cured influenza, pneumonia, and hepatitis. In the 1970s, Hugh D. Riordan, M.D., was obtaining cures of cancer with intravenous vitamin C. Dr. Harold Foster and colleagues arrested and reversed full-blown AIDS with nutrient therapy, and in just the last few years, Atsuo Yanagasawa, M.D., Ph.D., has shown that vitamin therapy can prevent and reverse sickness caused by exposure to nuclear radiation. Since 1968, much of this research has been published in the Journal of Orthomolecular Medicine. This book brings forward important material selected from over forty-five years of JOM directly to the reader.

The Orthomolecular Treatment of Chronic Disease is a very large book, but it is also a very practical book. If you want to know which illnesses best respond to nutrition therapy, and how and why that therapy works, this is the book for you. Part One presents the principles of orthomolecular medicine and the science behind them. Part Two is devoted to orthomolecular pioneers, presenting an introduction to maverick doctors and nutrition scientists in a reader-friendly way that brings the subject to life. Part Three brings together extraordinary clinical and experimental evidence from expert researchers and clinicians.

The Orthomolecular Treatment of Chronic Disease shows exactly how innovative physicians have gotten outstanding results with high-dose nutrient therapy. Their work is here for you to see and decide for yourself.

This book presents the latest evidence-based approaches to assessing and managing movement disorders in children. Uniquely, the authors have chosen to examine not just children with developmental coordination disorder, but also children with movement difficulties as a co-occurring secondary characteristic of another development disorder, including Attention Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, Specific language Impairment and Dyslexia. Guidelines are underpinned by motor learning theory, empiricism and professional practice. The authors have taken an ecological approach to management and show how professionals and carers working together can make relatively simple changes in a child's life that aggregate to substantial support. The book is rich in case studies to demonstrate the adaptability of these guidelines and show how they may be applied to children of different ages, abilities, and environments. The final chapter is comprised of interviews of thirteen notable clinicians and academics with intervention methodologies from around the world. This book is a valuable guide for anybody working with children with movement difficulties, including clinicians, teachers and parents.

It is now widely accepted that there are important links between inactivity and lifestyle-related chronic diseases, and that exercise can bring tangible therapeutic benefits to people with long-term chronic conditions. Exercise and Chronic Disease: An Evidence-Based Approach offers the most up-to-date survey currently available of the scientific and clinical evidence underlying the effects of exercise in relation to functional outcomes, disease-specific health-related outcomes and quality of life in patients with chronic disease conditions.

Drawing on data from randomized controlled trials and observational evidence, and written by a team of leading international researchers and medical and health practitioners, the book explores the evidence across a wide range of chronic diseases, including:

• cancer
• heart disease
• stroke
• diabetes
• parkinson's disease
• multiple sclerosis
• asthma.

Each chapter addresses the frequency, intensity, duration and modality of exercise that might be employed as an intervention for each condition and, importantly, assesses the impact of exercise interventions in relation to outcomes that reflect tangible benefits to patients. No other book on this subject places the patient and the evidence directly at the heart of the study, and therefore this book will be essential reading for all exercise scientists, health scientists and medical professionals looking to develop their knowledge and professional practice.

It is now widely accepted that there are important links between inactivity and lifestyle-related chronic diseases, and that exercise can bring tangible therapeutic benefits to people with long-term chronic conditions. Exercise and Chronic Disease: An Evidence-Based Approach offers the most up-to-date survey currently available of the scientific and clinical evidence underlying the effects of exercise in relation to functional outcomes, disease-specific health-related outcomes and quality of life in patients with chronic disease conditions. Drawing on data from randomized controlled trials and observational evidence, and written by a team of leading international researchers and medical and health practitioners, the book explores the evidence across a wide range of chronic diseases, including: cancer heart disease stroke diabetes parkinson's disease multiple sclerosis asthma. Each chapter addresses the frequency, intensity, duration and modality of exercise that might be employed as an intervention for each condition and, importantly, assesses the impact of exercise interventions in relation to outcomes that reflect tangible benefits to patients. No other book on this subject places the patient and the evidence directly at the heart of the study, and therefore this book will be essential reading for all exercise scientists, health scientists and medical professionals looking to develop their knowledge and professional practice.

The New England Journal of Medicine lauds Dr. W. Grant Thompson as "a gifted teacher and clinician with a talent for clear exposition". In the spirit of the highly acclaimed Gut Reactions, Dr. Thompson shares his expertise on how to cope with two widespread and debilitating diseases - colitis and Crohn's disease. These two chronic, nonfatal yet devastating ailments typically strike the young and may develop into a lifetime burden. Most patients are traumatized by their diagnosis and become frustrated and depressed by the recurring nature of these illnesses. As a result, caring and open communication between patient and doctor is essential. Perhaps more so than a physician in any other specialty, a gastroenterologist must be in tune with the mind and body of his patient. Dr. Thompson, an international expert and chief of a hospital gastroenterology unit, epitomizes this valuable quality and bestows the fruit of his knowledge and compassion on the reader. In addition to highlighting the significant similarities and differences of these two syndromes and stressing the importance of a correct diagnosis, Dr. Thompson broaches more sensitive topics that seem to be ignored by the medical profession. He explores the unique psychosocial and sexual concerns, as well as the effects of pregnancy on those women who suffer from these conditions. His gift for writing and warm, caring style make the daily struggles of these illnesses seem easier to bear. One of the worst consequences of these stubborn ailments is the accompanying reduction in the quality of life. Dr. Thompson addresses common worries about body image due to illness or surgery, loss of sexual drive or ability to perform, pain andsuffering, possible effects of medication, and concern over the ominous relationship between ulcerative colitis and cancer. In accessible and supportive prose, Dr. Thompson examines the pros and cons of all possible treatments including drug therapy, nutrition, and surgery. He outlines latest theories, attempting to pinpoint the still mysterious causes of these disorders. Take control of your disease under the authoritative guidance of Dr. Thompson and his dedicated, sensible approach. You will gain a new perspective on your "angry gut" and find the courage to thrive.

An intensive-care doctor reveals the long-term problems caused by ICUs, and how these can be prevented. Thousands of people are admitted to intensive-care units (ICUs) every day, and this is only increasing with the Covid-19 pandemic. Most of these admissions will be sudden, unexpected, and harrowing - an experience that can alter patients and their families in physical, emotional, and spiritual ways, with effects that endure for years. But there is hope. Dr Ely is a leading ICU doctor. His unconventional methods minimise patients being harmed by the cutting-edge technologies that are saving their lives; post-intensive care syndrome (PICS) is a well-established complication that millions of ICU survivors battle, which Dr Ely aims to eradicate. His cutting-edge studies have convinced doctors around the world to change their ICU practices for the better. Through captivating stories, Dr Ely shows how he and colleagues from around the world have re-introduced humanity into the ICU, creating pathways that bring hope and healing to healthcare. This is the future of medicine, and is a must-read for healthcare professionals, patients, and their families.

Targeting the key active elements in the mechanism and application of apoptosis and its therapeutic implications, Apoptosis: Modern Insights into Disease from Molecules to Man covers apoptosis from A to Z. Comprehensive in scope, it explores a wide range of topics including various cancers, asthma, and multiple sclerosis as well as alcohol induced liver disease, chronic back pain, and cardiovascular health. With 40 chapters written by highly respected authorities, this single source reference provides researchers and scientists with the foundation they need.

From an acclaimed author in the field, this is a compelling study of the origins and history of the disease commonly seen as afflicting young unmarried girls. Understanding of the condition turned puberty and virginity into medical conditions, and Helen King stresses the continuity of this disease through history, depsite enormous shifts in medical understanding and technonologies, and drawing parallels with the modern illness of anorexia. Examining its roots in the classical tradition all the way through to its extraordinary survival into the 1920s, this study asks a number of questions about the nature of the disease itself and the relationship between illness, body images and what we should call'normal' behaviour. This is a fascinating and clear account which will prove invaluable not just to students of classical studies, but will be of interest to medical professionals also

Call it a remnant of our Victorian past, but sexual concerns lag behind other aspects of health, both in the training of physicians and therapists and in the way they impart this knowledge to clients. But as sexuality gains recognition as crucial to one's quality of life, evidence-based methods of understanding and discussing sex are imperative-and not only in treating pathology. Sexual Medicine in Clinical Practice provides framework, rationale, and strategies for both approaching sexual problems and addressing patients' questions about sexual health, behavior, and relationships. Analyzing sexuality along three dimensions-attachment, reproduction, and desire-this concise manual offers a biopsychosocial lifespan model readily translatable into clinical work. This "syndyastic" framework integrates attachment and relational theory to reinforce the bond between intimacy and connectedness, and models nonjudgmental approaches to disorders of sexual function, maturity, preference, and behavior. The authors' salutogenic rather than pathogenic focus lets clients become major players in their own healing, and the therapist or doctor serve as expert and guide. Among the topics covered: The communicative function of sexuality. The spectrum of sexual disorders. Principles of diagnostics in sexual medicine. Disease-centered versus client-centered aspects of sexual therapy. Therapeutic approaches for sexual traumatization. New challenges, including preventing child sexual abuse and online sex crime. Plus case studies, interdisciplinary references, and ethical issues. A timely, perspective- and practice-altering volume, Sexual Medicine in Clinical Practice is essential reading for family and primary care physicians, family and sex therapists, health psychologists, and psychiatrists.

This completely revised and updated second edition to integrates the many new technologies and insights now available for the diagnosis of genetic diseases. The authors use such methodologies as PCR optimization dosage analysis, mutation scanning, and quantitative fluorescent PCR for aneuploidy analysis, Neurofibromatosis type 1, and Duchenne muscular dystrophy. These largely generic methodologies may be adapted to most genetic conditions for which a molecular diagnosis is relevant, no matter how frequent or rare their incidence. Molecular Diagnosis of Genetic Diseases, Second Edition offers diagnostic molecular geneticists a unique opportunity to sharpen their scientific skills in the design of assays, their execution, and their interpretation.

Following the core principle of phenomenology as a return "to the things themselves," Body Matters attends to the phenomena of bodily afflictions and examines them from three different standpoints: from society in general that interprets them as "sicknesses," from the medical professions that interpret them as "diseases," and from the patients themselves who interpret them as "illnesses." By drawing on a crucial distinction in German phenomenology between two senses of the body the quantifiable, material body (Korper) and the lived-body(Leib) the authors explore the ways in which sickness, disease, and illness are socially and historically experienced and constructed. To make their case, they draw on examples from a multiplicity of disciplines and cultures as well as a number of cases from Euro-American history. The intent is to unsettle taken-for-granted assumptions that readers may have about body troubles. These are assumptions widely held as well by medical and allied health professionals, in addition to many sociologists and philosophers of health and illness. To this end, Body Matters does not simply deconstruct prejudices of mainstream biomedicine; it also constructively envisions more humane and artful forms of therapy."