This book is an introductory text to spinal disorders. Based on the highly successful forerunner to this volume, Practical Orthopaedic Medicine, the book still retains the original philosophy of this text which is to systematically cover all the joints discussing examination, diagnosis and treatment. The full spectrum of therapies is covered with particular emphasis on Maitland's widely practised spinal manipulation techniques - how they are assessed clinically and their role in the management of spinal problems. A complete review of the current literature has been undertaken and a valuable new chapter on the spine in sport has been added. This book will be essential reading for students and practitioners involved in sports medicine, orthopaedic medicine and physiotherapy.

This text highlights the value of a team approach to appreciating the commplexity of spinal pain and a range of treatment approaches. Contributions from epidemiology, anatomy, pathology, biomechanics, clinical medicine orthopaedics, chiropractic, osteopathy and physiotherapy are presented. Each section is written by an experienced practitioner and provides a summary of pertinent material, seeking to improve the reader's understanding of the causes of cervical spine pain The volume is part of a series of three books bringing together a multidisciplinary approach to the management of mechanical spinal pain.

Metabolic Bone Disease, Third Edition is the new, expanded edition of the classic text, featuring the latest advancements and research information in this fast-moving field. The Third Edition includes the most up-to-date information on molecular mechanisms, basic biology, pathophysiology, and diagnosis and management strategies of metabolic bone disease.
Key Features
* Edited by "fathers of the field"
* An expanded version of a classic AP text
* Complete coverage of a fast-growing field

Atrial fibrillation is a heart condition that causes an irregular and often abnormally fast heart rate. It can cause problems including dizziness, shortness of breath and tiredness and a patient may be aware of noticeable heart palpitations, where the heart feels like it is pounding, fluttering or beating irregularly, often for a few seconds or, in some cases, a few minutes (NHS Choices). This comprehensive guide presents clinicians with the latest developments in the diagnosis and management of atrial fibrillation. Divided into seven sections, the book covers clinical spectrum, diagnosis, therapeutic strategies, interventions, and new technologies used in its treatment and prevention. Complete sections are dedicated to other arrhythmias, to cardiac surgery and to future directions in atrial fibrillation. With more than 1000 pages providing in depth coverage of the topic, this manual is further enhanced by clinical photographs, diagrams and tables. Key Points Comprehensive guide to latest developments in diagnosis and treatment of atrial fibrillation More than 1000 pages discuss clinical spectrum, diagnosis, treatment options, interventions, and new technologies Complete sections dedicated to other arrhythmias, cardiac surgery, and future directions Highly illustrated with clinical photographs, diagrams and tables

'Billy Connolly says he's no idea who Parkinson was and just wishes he'd kept his disease to himself. He should read this book.' Jeremy Paxman Parkinson's disease is one of the most common forms of dementia, with 10,000 new cases each year in the UK alone, and yet few know anything about the man the disease is named after. In 1817 - exactly 200 years ago - James Parkinson (1755-1824) defined the disease so precisely that we still diagnose it today by recognising the symptoms he identified. The story of this remarkable man's contributions to the Age of the Enlightenment is told through his three passions - medicine, politics and fossils. As a political radical Parkinson was interrogated over a plot to kill King George III and revealed as the author of anti-government pamphlets, a crime for which many were transported to Australia; while helping Edward Jenner set up smallpox vaccination stations across London, he wrote the first scientific study of fossils in English, which led to fossil-hunting becoming the nation's latest craze - just a glimpse of his many achievements. Cherry Lewis restores this neglected pioneer to his rightful place in history, while creating a vivid and pungent portrait of life as an 'apothecary surgeon' in Georgian London.

Vitamin D deficiency, circulating levels lower than 15 ng/ml, is an epidemic disease worldwide with more than a billion people suffering of it in the beginning of the 21-century. Besides its impact on mineral and bone metabolism, these low vitamin D levels are also associated with a diversity of non-skeletal complications, among them cardiovascular disease, diabetes mellitus, multiple sclerosis, cancer, tuberculosis, and immune system dysfunction. Chronic Kidney Disease is also a very common disease, affecting more than 10% of the world population, ranging from stage 1 to stage 5 before dialysis. Approximately 1% of the population in industrialized countries is affected by end-stage renal disease (ESRD), needing a renal replacement therapy either hemodialysis or peritoneal dialysis, and ultimately by renal transplantation. Those CKD patients are more susceptible to exhibit reduced vitamin D stocks. Consequently, more than eighty percent of CKD patients have either insufficient or deficient vitamin D levels for multiple reasons.

This book addresses the ever increasing problem of obesity in children and adolescents, the long-term health and social problems that arise from this, and approaches to prevention and management. Aimed at doctors, and all health-care professionals, it will be of interest to all those concerned with the increasing prevalence of obesity in both the developed and developing world. It covers all aspects of obesity from epidemiology and prevention to recent developments in biochemistry and genetics, and to the varied approaches to management which are influenced by social and clinical need. A foreword by William Dietz and a forward-looking 'future perspectives' conclusion by Philip James embrace an international team of authors, all with first-hand experience of the issues posed by obesity in the young. This comprehensive survey of an important and growing medical problem will help inform, influence and educate those charged with tackling this crisis.

Noncommunicable diseases (NCDs) - including cardiovascular disease, diabetes, asthma and other chronic respiratory conditions, and cancers - are the leading causes of death worldwide. An estimated 36 million people die from such diseases each year; this represents roughly two out of three deaths globally. Eighty percent of these fatalities occur in developing countries. The statistics are staggering, yet millions of these deaths are preventable. This is an urgent global health issue that demands analysis of gaps in NCD research, new policies and practices, and actionable recommendations to close the gaps. The Johns Hopkins Institute for Applied Economics, Global Health, and the Study of Business Enterprise convened an NCD Working Group of leading scholars to examine a wide range of issues that both the private and public sectors must address to make sustainable progress in NCD prevention and treatment in lower- and middle-income countries. Collected in this volume are essays on five key areas where strengthened policies and health systems can have the most impact in the near future. Features: accelerating regulatory harmonization; structuring supply chains; improving access to interventions; restructuring primary care; and promoting multisectoral and intersectoral action. While there is a growing literature on the problem of NCDs, none of the available studies provides background on the range of challenges matched with specific steps that can be taken by the public sector, private sector, and civil society working together. Noncommunicable Diseases in the Developing World presents a framework for understanding the salience of specific policy recommendations and detailed steps that can be taken now to move forward in the global campaign against NCDs. This book will be of interest to practitioners, scholars, and students in public health as well as those framing and implementing health policies in the private and public sectors.

This clinical guide describes a different way to treat borderline personality disorder. Rather than using the currently available therapies, the author presents a trans-theoretical approach that combines the essential elements of all effective treatments. The book offers a framework for understanding the nature and origins of borderline personality disorder that is used to define treatment targets and strategies. Building on this foundation, systems for organizing treatment are presented around change mechanisms common to all effective therapies. Interventions are presented in modules, allowing therapists to select treatment according to the needs of patients. Treatment is explained by dividing therapy into phases, each addressing different problems. Methods are described to promote engagement, manage suicidality, treat crises, improve emotional regulation, restructure maladaptive interpersonal behaviours, construct a new sense of self and identity, and build a life worth living. The volume will interest mental health professionals from all disciplines and different levels of expertise.

This user-friendly clinical handbook provides a clear and concise overview of how to go about recognizing and diagnosing inherited metabolic diseases. The reader is led through the diagnostic process from the identification of those features of an illness suggesting that it might be metabolic through the selection of appropriate laboratory investigation to a final diagnosis. The book is organized into chapters according to the most prominent presenting problem of patients with inherited metabolic diseases: neurologic, hepatic, cardiac, metabolic acidosis, dysmorphism, and acute catastrophic illness in the newborn. It also includes chapters on general principles, laboratory investigation, neonatal screening, and the principles of treatment. This new edition includes much greater depth on mitochondrial disease and congenital disorders of glycosylation. The chapters on neurological syndrome and newborn screening are greatly expanded, as are those on laboratory investigation and treatment, to take account of the very latest technological developments.

The past few years have witnessed rapid progress in the characterization of mechanisms that underlie the generation and processing of inter- and intracellular signals. While there have been significant corollary advances in the area of signaling in disease processes, there is as yet no single resource that connects these advances with an understanding of disease processes and applications for novel therapeutics. Collecting chapters from the leading experts in their respective fields, editors Toren Finkel and Silvio Gutkind deliver a much-needed introduction to signaling and a fruitful discussion of promising directions for future research.

Signal Transduction and Human Disease capitalizes on the current emphasis on translational research and biological relevance in biotechnology and, conversely, the importance of molecular approaches for clinical research. Each chapter conveys the sense of a disease process, what it affects, how it presents, how common it is, and what the treatments are. Clinical descriptions are not exhaustive but rather serve as an outline regarding the disease’s manifestations and current treatment options. Following this introduction, the authors present an in-depth discussion of one or two signal transduction pathways or biological processes relevant to the disease. The editors divide their study into five sections:

• Cardio-Pulmonary Disease
• Oncology
• Endocrinology
• Infectious Disease
• Allergy/Rheumatology
• Neurology/Psychiatry

Biochemists, molecular and cell biologists, immunologists, pharmacologists, and clinical researchers, as well as graduate students in a variety of scientific disciplines, will find Signal Transduction and Human Disease to be an invaluable addition to the literature.

The Cambridge World History of Human Disease (CWHHD) was first published by Cambridge in 1993. The basis of this Dictionary is Part VIII, the last section of the work, that comprises a history and description of the world's major diseases of yesterday and today in chapters organized alphabetically from "Acquired Immune Deficient Syndrome (AIDS)" to "Yellow Fever." The last section of CWHHD has been fully revised and the essays have been condensed into shorter entries, with up-to-date information on AIDS, Alzheimer's disease, Ebola, and Tuberculosis. The Dictionary also includes three chapters from other parts of the CWHHD on "Heart-Related Diseases," "Cancer," and Genetic Disease." Including contributions from over 100 medical and social scientists worldwide, the Dictionary is a truly interdisciplinary history of medicine and human disease. Kenneth Kiple is a distinguished professor of history at Bowling Green State University. His research and teaching interests include Latin America and the history of medicine, disease, and nutrition. His work has been supported by grants and fellowships from the Guggenheim Foundation, the National Endowment for the Humanities, the Fulbright Foundation, the American Council of Learned Societies, the American Philosophical Society, and the National Institutes of Health. He is the editor of The Cambridge History of World Disease (Cambridge, 1993) and with Kriemhild Coneé Ornelas, the award-winning Cambridge World History of Food (Cambridge, 2000).

This book describes and discusses the assessment and treatment techniques applied by Occupational Therapists (OTs) to sufferers from Multiple Sclerosis (MS). The text begins with basic information about MS and follows this with suggestions for assessment and treatment. Then the specific issues of work, fatigue, leisure, mobility and the home are considered in detail. The needs of people who reach the later stages of the disease are discussed, as are the needs and concerns specific to carers of those with MS. Contact details are provided for many of the services and agencies mentioned in the text. Insight into the impact of MS on peoplea s lives is provided by individuals with MS.

This extremely important book is the comprehensive and authoritative independent consensus report of the British Nutrition Foundation's Task Force on Obesity. The Task Force was invited by the Council of the British Nutrition Foundation to review the present state of knowledge of the causes, consequences, prevention and treatment of obesity and to prepare a report and, should it see fit, to draw conclusions, make recommendations and identify areas for future research.

Obesity is an authoritative and definitive landmark publication covering all major aspects of this vitally important condition. Bringing together a huge wealth of research information from a wide variety of disciplines, in a well-presented, clear and carefully-edited format, Obesity is an indispensable guide for all personnel involved in the prevention and treatment of obesity, or for those studying and researching in this area. The book provides comprehensive coverage of the health risks, clinical assessment, epidemiology, aetiology, prevention and treatment of obesity.

Furthermore, the Task Force makes important recommendations, which should be considered by all those involved in this area.

Obesity provides core information for health professionals, including nutritionists, dietitians, nurses, family or general practitioners, physicians and sports scientists, and lecturers, undergraduates, postgraduates and postdoctoral researchers in nutrition, dietetics and related subjects.

Personnel in the pharmaceutical and food industry responsible for the development of special dietary products and medicines for use in the prevention and treatment of obesity as well as those involved in health promotionwill find this work to be an extremely valuable reference. Obesity should also be available on the shelves of all libraries in universities, medical schools and medical, nutrition and food science research establishments.

Cough is the most familiar symptom of respiratory disease, and a problem which general practitioners must deal with on a daily basis. This timely volume draws together a wealth of recent research into the mechanisms, pharmacology and therapies for cough, and places these in clinical context. The text incorporates guidelines on the most common causes of cough, discusses treatments and pitfalls in management, summarizes current research on physiology, pharmacology and treatment of cough, and gives practical advice on diagnosis and management issues for the clinician. "Cough: Causes, Mechanisms and Therapy" is the most comprehensive, up-to-date account of the subject.It will update clinical and basic medical scientists, and promote future research. Readers are encouraged to implement the clinical implications of the discussion into routine practice. This volume will appeal to all those involved in the treatment of respiratory disease, particularly those in hospital respiratory units, and will also be of use to interested general practitioners.

Making Sense of Illness is a fascinating investigation into the social and clinical factors that determine what constitutes a "legitimate" illness in the twentieth century. By examining six case studies of diseases that have emerged within the past fifty years--from what we now consider to be "straightforward" diseases such as coronary heart disease, to the currently widely-debated Chronic Fatigue Syndrome--Aronowitz examines the historical and cultural factors that influence how doctors think about illness; how illnesses are recognized, named, classified, and finally, what they "mean" in an individual and social context. The choices that are available to the investigators, clinicians, patients and the processes by which change occurs are factors that all play a great role in "legitimizing" an illness, and these are the roles that are seldom examined. By juxtaposing the histories of each disease, Aronowitz shows how cultural and historical precedents have determined research programs, public health activities, clinical decisions, and even the patient's experience of illness. This is a must-read for anyone interested in public health and the history of medicine in the United States.

Disease-related malnutrition is a global public health problem. The consequences of disease-related malnutrition are numerous, and include shorter survival rates, lower functional capacity, longer hospital stays, greater complication rates, and higher prescription rates. Nutritional support, in the form of oral nutritional supplements or tube feeding, has proven to lead to an improvement in patient outcome. This book is unique in that it draws together the results of numerous different studies that demonstrate the benefits of nutritional support and provides an evidence base for it. It also discusses the causes, consequences, and prevalence of disease-related malnutrition, and provides insights into the best possible use of enteral nutritional support.

Functional somatic syndromes are defined as physical syndromes without an organic disease explanation, demonstrable structural changes, or established biochemical abnormalities. This book reviews the state of scientific and clinical understanding of the nine most common functional somatic syndromes. For each syndrome, expert contributors provide a brief historical perspective, a current definition, a case presentation, confirmatory and contradictory research findings, a discussion of the leading pathogenetic hypotheses, and guidelines for diagnosis and treatment. Chapters offer advice for the determination of disability of patients with these medically unexplained disorders, while describing both medical and psychiatric interventions. Stressing the importance of a sound therapeutic relationship as a basis for treatment, this is an invaluable resource for professionals in primary care and many other disciplines.

This new edition of The Handbook of Memory Disorders has been completely rewritten to reflect the huge amount of new research in recent years on both the understanding of memory disorders and the assessment and treatment of patients. Written by a truly international team of experts, it offers an authoritative review of the key areas of research and development in this field.

Highlights of the second edition include:

• a new section on developmental memory disorders

• new chapters on frontal lobe deficits, confabulation and the neuropsychological basis of false memory

• discussion of research on animals and computational modelling

• a new chapter that overviews structural and functional imaging techniques.

This Handbook continues to be an invaluable resource for academics, professionals, practitioners and trainees in cognitive and clinical psychology, psychiatry, neurology, speech and occupational therapy, and other related fields.

From Dr. Jennifer Ashton-the Chief Medical Correspondent at ABC News covering breaking medical news for Good Morning America and GMA3: What You Need to Know-comes a doctor's guide to finding resilience in the time of COVID, while staying safe and sane in a rapidly changing world. In March 2020, "normal" life changed, perhaps forever. In its place we were confronted with life and routines that were unusual and different: the new normal. As we've all learned since then, the new normal isn't just about wearing masks and standing six feet apart-it's about recognizing how to stay safe and sane in a world that is suddenly unfamiliar. And no one understands this evolving landscape better than Dr. Jennifer Ashton. As ABC's Chief Medical Correspondent, Dr. Ashton has been reporting on the novel coronavirus daily, helping Americans comprehend the urgent medical updates that have shaped the nation's continued response to this public health crisis. Now in The New Normal, Dr. Ashton offers the essential toolkit for life in this unfamiliar reality. Rooted in her reporting on COVID-19 and the understanding that the virus isn't going anywhere overnight, The New Normal is built on a simple foundation: thriving in this evolving world demands accepting the new normal for what it is, not what we want it to be. No longer is wellness a buzzword, but an imperative for surviving this unprecedented time. Using her trademark practical, easy-to-follow advice, Dr. Ashton gives you all the necessary information to reclaim control of your life and live safely-from exercise, to diet, to general health-showing how to prepare your body and mind for challenges such as: - Taking proper medical precautions to protect yourself and your loved ones - Exercising during the pandemic, even if you no longer feel safe at the gym - Finding emotional balance through these uncertain times - Deciphering complicated medical news to learn what to trust and what to ignore With these straightforward and accessible strategies and many more, Dr. Ashton helps empower you to make the unexpectedly hard decisions about socializing, food-shopping, seeing doctors, and most of all, finding normalcy. At once reassuring and urgent, The New Normal is a holistic roadmap through the ongoing struggles of the pandemic, providing the guidance you need to navigate this unsettling time and take charge of your future wellbeing.

Author of the international bestsellers The Diabetes Code and The Obesity Code Dr. Jason Fung returns with an eye-opening biography of cancer in which he offers a radical new paradigm for understanding cancer—and issues a call to action for reducing risk moving forward. Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline . . . but the “War on Cancer� has hardly been won. In The Cancer Code, Dr. Jason Fung offers a revolutionary new understanding of this invasive, often fatal disease—what it is, how it manifests, and why it is so challenging to treat. In this rousing narrative, Dr. Fung identifies the medical community’s many missteps in cancer research—in particular, its focus on genetics, or what he terms the “seed� of cancer, at the expense of examining the “soil,� or the conditions under which cancer flourishes. Dr. Fung—whose groundbreaking work in the treatment of obesity and diabetes has won him international acclaim—suggests that the primary disease pathway of cancer is caused by the dysregulation of insulin. In fact, obesity and type 2 diabetes significantly increase an individual’s risk of cancer. In this accessible read, Dr. Fung provides a new paradigm for dealing with cancer, with recommendations for what we can do to create a hostile soil for this dangerous seed. One such strategy is intermittent fasting, which reduces blood glucose, lowering insulin levels. Another, eliminating intake of insulin-stimulating foods, such as sugar and refined carbohydrates. For hundreds of years, cancer has been portrayed as a foreign invader we’ve been powerless to stop. By reshaping our view of cancer as an internal uprising of our own healthy cells, we can begin to take back control. The seed of cancer may exist in all of us, but the power to change the soil is in our hands.