This book constitutes the thoroughly refereed post-conference proceedings of the 10th International Conference on Large-Scale Scientific Computations, LSSC 2015, held in Sozopol, Bulgaria, in June 2015. The 49 revised full papers presented were carefully reviewed and selected from 64 submissions. The general theme for LSSC 2015 was Large-Scale Scientific Computing with a particular focus on the organized special sessions: enabling exascale computation; control and uncertain systems; computational microelectronics - from monte carlo to deterministic approaches; numerical methods for multiphysics problems; large-scale models: numerical methods, parallel computations and applications; mathematical modeling and analysis of PDEs describing physical problems; a posteriori error control and iterative methods for maxwell type problems; efficient algorithms for hybrid HPC systems; multilevel methods on graphs; and applications of metaheuristics to large-scale problems.

Explore the miracles of the microscopic world. Find out all about the unique and beautiful kingdoms of life at a microscopic scale and how every organism meets the challenges of survival no matter its size. The perfect book for people who enjoy photography, nature, and biology. Inside the pages of this exciting nature book, you'll find: - Microscopic life-forms (often neglected), and their larger life-forms in extreme close-ups, revealing details such as nerve cells and hair follicles - Artworks support the beautiful images, providing a deeper insight into structure and function and building a picture of how living organisms work at a microscopic level - Comprehensive coverage of the natural world, including all the main groups of living things - Explores overlooked groups that have a huge role in the natural world: insects, which make up 80 percent of the world's animal species; and bacteria - of which there are more in a human mouth than there are people in the world - The book is organised according to the main functions of life: movement, reproduction, energy and feeding, sensing the surroundings, defence, etc. - Foreword for the book written by Chris Packham Explore the inhabitants of an invisible world in incredible detail with this book which contains macro photography and spectacular microscope imagery. You'll have so much information about the hidden world of intricate structures beyond the naked eye. From the tiniest spiders and insects to even microscopic creatures such as bacteria and viruses, this book contains it all! See the beauty of a pollen grain, a butterfly egg, the spore of a fungus, and a human's nerve cell in extreme close up. The amazing imagery in Micro Life contains focus-stacked macro photographs and micrographs (microscope images), including scanning electron micrographs. Illustrations in this book explain the science - from the workings of an insect's eye to how a plant "breathes" through its leaves. Micro Life is an unexpectedly breathtaking look at the natural world. Find out how life works and how organisms solve the fundamental problems of movement, reproduction, energy, communication, and defence. Suitable for all the family, this stunning book makes a wonderful gift for those interested in photography, nature or biology.

Prudent Practices in the Laboratory-the book that has served for decades as the standard for chemical laboratory safety practice-now features updates and new topics. This revised edition has an expanded chapter on chemical management and delves into new areas, such as nanotechnology, laboratory security, and emergency planning. Developed by experts from academia and industry, with specialties in such areas as chemical sciences, pollution prevention, and laboratory safety, Prudent Practices in the Laboratory provides guidance on planning procedures for the handling, storage, and disposal of chemicals. The book offers prudent practices designed to promote safety and includes practical information on assessing hazards, managing chemicals, disposing of wastes, and more. Prudent Practices in the Laboratory will continue to serve as the leading source of chemical safety guidelines for people working with laboratory chemicals: research chemists, technicians, safety officers, educators, and students. Table of Contents Front Matter 1 The Culture of Laboratory Safety 2 Environmental Health and Safety Management System 3 Emergency Planning 4 Evaluating Hazards and Assessing Risks in the Laboratory 5 Management of Chemicals 6 Working with Chemicals 7 Working with Laboratory Equipment 8 Management of Waste 9 Laboratory Facilities 10 Laboratory Security 11 Safety Laws and Standards Pertinent to Laboratories Bibliography APPENDIXES Appendix A: OSHA Laboratory Standard Appendix B: Statement of Task Appendix C: Committee Member Biographies Index

This DK children's book aged 11-14 is brimming with exciting, educational activities and projects that focus on electronics and technology.

Keep your siblings out of your room with a brilliant bedroom alarm, power a propellor motorboat, make a stereo from pipes, build your own AM radio, and construct a night light by following step-by-step instructions and using affordable equipment. Inventor Lab will engage budding scientists and engineers as they experiment, invent, trial, and test technology, electronics, and mechanics at home.

Simple steps with clear photographs take readers through the stages of each low-cost project, with fact-filled "How it works" panels to explain the science behind each one, and to fascinate them with real-world examples.

With an increasing focus across school curricula on encouraging children to enjoy and explore STEM subjects (science, technology, engineering, and maths), Inventor Lab is the perfect companion for any inquisitive child with an interest in how the worlds of science experiments and technology work, and why.

Passive acoustic monitoring is increasingly used by the scientific community to study, survey and census marine mammals, especially cetaceans, many of which are easier to hear than to see. PAM is also used to support efforts to mitigate potential negative effects of human activities such as ship traffic, military and civilian sonar and offshore exploration. Walter Zimmer provides an integrated approach to PAM, combining physical principles, discussion of technical tools and application-oriented concepts of operations. Additionally, relevant information and tools necessary to assess existing and future PAM systems are presented, with Matlab code used to generate figures and results so readers can reproduce data and modify code to analyse the impact of changes. This allows the principles to be studied whilst discovering potential difficulties and side effects. Aimed at graduate students and researchers, the book provides all information and tools necessary to gain a comprehensive understanding of this interdisciplinary subject.

Originally published in 1941, this book seeks to inform the scientific community of the possible uses of photography in research or teaching. Lawrence gives an account of the possibilities and limitations of the medium for the scientific reader as well as for the 'serious amateur', explains the various mechanisms of the camera and gives some suggestions for scientific applications, such as high-speed photography. This book will be of value to anyone with an interest in photography or the history of science.

Written for animal researchers, this book provides a comprehensive guide to the design and statistical analysis of animal experiments. It has long been recognised that the proper implementation of these techniques helps reduce the number of animals needed. By using real-life examples to make them more accessible, this book explains the statistical tools employed by practitioners. A wide range of design types are considered, including block, factorial, nested, cross-over, dose-escalation and repeated measures and techniques are introduced to analyse the experimental data generated. Each analysis technique is described in non-mathematical terms, helping readers without a statistical background to understand key techniques such as t-tests, ANOVA, repeated measures, analysis of covariance, multiple comparison tests, non-parametric and survival analysis. This is also the first text to describe technical aspects of InVivoStat, a powerful open-source software package developed by the authors to enable animal researchers to analyse their data and obtain informative results.

Recent developments in scanning electron microscopy (SEM) have resulted in a wealth of new applications for cell and molecular biology, as well as related biological disciplines. It is now possible to analyze macromolecular complexes within their three-dimensional cellular microenvironment in near native states at high resolution, and to identify specific molecules and their structural and molecular interactions. New approaches include cryo-SEM applications and environmental SEM (ESEM), staining techniques and processing applications combining embedding and resin-extraction for imaging with high resolution SEM, and advances in immuno-labeling. New developments include helium ion microscopy, automated block-face imaging combined with serial sectioning inside an SEM chamber, and Focused Ion Beam Milling (FIB) combined with block-face SEM. With chapters written by experts, this guide gives an overview of SEM and sample processing for SEM, and highlights several advances in cell and molecular biology that greatly benefited from using conventional, cryo, immuno, and high-resolution SEM.

For most of the history of scientific endeavour, science has been recorded on paper. In this digital era, however, there is increasing pressure to abandon paper in favour of digital tools. Despite the benefits, there are barriers to the adoption of such tools, not least their usability. As the relentless development of technology changes the way we work, we need to ensure that the design of technology not only overcomes these barriers, but facilitates us as scientists and supports better practice within science. This book examines the importance of record-keeping in science, current record-keeping practices, and the role of technology for enabling the effective capture, reuse, sharing, and preservation of scientific data. Covering the essential areas of electronic laboratory notebooks (ELNs) and digital tools for recording scientific data, including an overview of the current data management technology available and the benefits and pitfalls of using these technologies, this book is a useful tool for those interested in implementing digital data solutions within their research groups or departments. This book also provides insight into important factors to consider in the design of digital tools such as ELNs for those interested in producing their own tools. Finally, it looks at the role of current technology and then considers how that technology might develop in the future to better support scientists in their work, and in capturing and sharing the scientific record.

The fundamental principles of the scientific method are essential for enhancing perspective, increasing productivity, and stimulating innovation. These principles include deductive and inductive logic, probability, parsimony and hypothesis testing, as well as science's presuppositions, limitations, ethics and bold claims of rationality and truth. The examples and case studies drawn upon in this book span the physical, biological and social sciences; include applications in agriculture, engineering and medicine; and also explore science's interrelationships with disciplines in the humanities such as philosophy and law. Informed by position papers on science from the American Association for the Advancement of Science, National Academy of Sciences and National Science Foundation, this book aligns with a distinctively mainstream vision of science. It is an ideal resource for anyone undertaking a systematic study of scientific method for the first time, from undergraduates to professionals in both the sciences and the humanities.

Succeed in biology with LABORATORY MANUAL FOR NON-MAJORS BIOLOGY! Through hands-on lab experience, this biology laboratory manual reinforces biology concepts to help you get a better grade. Exercises, pre-lab questions, and post-lab questions enhance your understanding and make lab assignments easy to complete and easy to comprehend.

This book was first published in 2006. The standard model brings together two theories of particle physics in order to describe the interactions of subatomic particles, except those due to gravity. This book uses the standard model as a vehicle for introducing quantum field theory. In doing this the book also introduces much of the phenomenology on which this model is based. The book uses a modern approach, emphasizing effective field theory techniques, and contains brief discussions of some of the main proposals for going beyond the standard model, such as seesaw neutrino masses, supersymmetry, and grand unification. Requiring only a minimum of background material, this book is ideal for graduate students in theoretical and experimental particle physics. It concentrates on getting students to the level of being able to use this theory by doing real calculations with the minimum of formal development, and contains several problems.

The most comprehensive textbook and detailed presentation of the lab techniques organic chemistry students need to know. Compatible with any organic chemistry lab manual or set of experiments, it combines specific instructions for three different kinds of laboratory glassware: miniscale, standard taper microscale, and Williamson microscale. This title provides effective support to all those looking for guided-inquiry and design-based experiments and projects, as well as for traditional lab experiments. This title is for organic students of all levels looking to improve and understand their knowledge of lab work. With new authors David Alberg and Gretchen Hofmeister on board for this fourth edition, both bring copious amounts of experience in organic chemistry. They have been able to revive the writing in the book, while also adding new examples and pitfalls for students to avoid.

The careful explanation of each step of the dissection, helpful diagrams and illustrations, and detailed discussion of the structure and function of each system in "Anatomy and Dissection of the Fetal Pig, Fifth Edition, " optimize the educational value of the dissection process. These laboratory exercises are sold separately or as a bound set. This popular series, which includes "Anatomy and Dissection of the Rat" and "Anatomy and Dissection of the Frog" is geared toward introductory courses in biology and comparative anatomy.
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Maria Rentetzi surveys the experimental practices of radioactivity research in early-twentieth-century Vienna, focusing on radioactive materials, instruments, women's work in physics, and gendered skills. She shows how experimental cultures in radioactivity-scientific practices employed by gendered subjects who shared a certain material and epistemic style of research--were constructed and reshaped by socialist politics in Vienna at that time. She also explores the different ways experimental practices affected men and women in laboratory sciences. Rentetzi expands the notion of material culture to include not only instruments and objects but also materials that operated as both commodities and objects of scientific inquiry. She tells a multifaceted story of how purified radium ended up on laboratory benches and who extracted and isolated it from tons of residues; the individuals who designed experiments and instruments for probing radium's properties; and those who carried radium outside of the physics laboratory and into the clinic and medical amphitheatres. Rentetzi examines how the architecture of the laboratory affected men's and women's scientific work and the way in which its urban setting reflected assumptions about scientific cross-disciplinary collaborations. Following the circulation of radium and the pursuit of power through strategies of partnership and collaboration, Rentetzi redraws paths of scientific exchange and transfers the reader from scientific laboratories to hospitals and from academic to industrial sites.

The measurement of metabolic rates is central to important questions in many areas of physiological research. Unfortunately these measurements are anything but straightforward, with numerous pitfalls awaiting both the novice and even the experienced investigator. The original edition of this work, published in 2008, quickly became the principle "how to" manual for the field. It successfully de-mystified the topic, explaining every common variation of metabolic rate measurement. Background information on different analyzer and equipment types allowed users to choose the best instruments for their application. Respirometry equations, normally a topic of terror and confusion to researchers, were derived and described in sufficient detail to facilitate their selection and use. In this new edition, the content has been thoroughly updated and a decade of new literature incorporated. New chapters on room calorimetry, human metabolic measurement, and metabolic phenotyping have also been added.

The market leader for the full-year organic laboratory, this manual derives many experiments and procedures from the classic Feiser lab text, giving it an unsurpassed reputation for solid, authoritative content. The book includes new experiments that stress greener chemistry, updated NMR spectra, and a Premium Website that includes glassware-specific videos with pre-lab exercises. Offering a flexible mix of macroscale and microscale options for most experiments, this proven manual allows users to save on the purchase and disposal of expensive, sometimes hazardous organic chemicals. Macroscale versions can be used for less costly experiments, giving readers experience working with conventionally sized glassware.

What can you learn about your world in just a moment? Have you ever wondered why the sky is blue? Or whether dogs can read our facial expressions? Don Glass and experts in their fields answer these questions and many more. Written for readers of all ages with no background in science required, How the World Looks to a Bee is the perfect armchair companion for curious people who want to know more about the science of everyday life but have only a moment to spare. With intriguing everyday phenomena as a starting point, this entertaining collection uses short tutorials and quick and simple experiments to invite readers to test the science for themselves. These fascinating and topical science stories are sure to delight the curious child in all of us.

Medical researchers including doctors, nurses, medical students and allied health professionals are required to undertake a period of research as part of their career pathway. This book covers the main areas, allowing anyone to set up and complete research projects and this information can easily be translated to clinical projects. Written by international authors to provide a flavor from many institutions, the booka (TM)s appeal is cross-sectional, both at hospital and primary care levels worldwide.

Section A, the most important area in the book, covers the hardest step - setting up research (i.e. initial paperwork and funding projects). Section B is technical, covering modern laboratory techniques for laboratory-based research. Section C tackles data collation and analysis and the presentation of the results (oral and written).

The book is directed at all doctors, medical students, and individuals in related specialities, either in research or considering research (e.g. MD, PhD, MSc and Intercalated BSc).

This book aims to provide an introduction to the major techniques of chemoinformatics. It is the first text written specifically for this field. The first part of the book deals with the representation of 2D and 3D molecular structures, the calculation of molecular descriptors and the construction of mathematical models. The second part describes other important topics including molecular similarity and diversity, the analysis of large data sets, virtual screening, and library design. Simple illustrative examples are used throughout to illustrate key concepts, supplemented with case studies from the literature.

Flow cytometry is now well established in research laboratories and is gaining increasing use in clinical medicine and pathology. The technique enables multiple simultaneous light scatter and fluorescence measurements to be made at the individual cell level at very rapid rates and results in very large quantities of data being collected. Data, however, is just a series of numbers which have to be converted to information which, in turn, must be shown to have meaning. This is the most important single aspect of flow cytometry but it has received relatively little attention. One of the frequently voiced advantages of the technology is that it produces 'good statistics' because large numbers of cells have been analysed. However, it is not very often that confidence limits are placed on results, hence the reader has little or no feel for the inherent variability in the information produced. This book covers very basic number handling techniques, regression analysis, probability functions, statistical tests and methods of analysing dynamic processes. All those who use flow cytometry in their research will find this book an invaluable guide to interpreting the data produced by flow cytometers.

For students, DIY hobbyists, and science buffs, who can no longer get real chemistry sets, this one-of-a-kind guide explains how to set up and use a home chemistry lab, with step-by-step instructions for conducting experiments in basic chemistry - not just to make pretty colors and stinky smells, but to learn how to do real lab work: purify alcohol by distillation; produce hydrogen and oxygen gas by electrolysis; smelt metallic copper from copper ore you make yourself; analyze the makeup of seawater, bone, and other common substances; synthesize oil of wintergreen from aspirin and rayon fiber from paper; perform forensics tests for fingerprints, blood, drugs, and poisons; and much more.From the 1930s through the 1970s, chemistry sets were among the most popular Christmas gifts, selling in the millions. But two decades ago, real chemistry sets began to disappear as manufacturers and retailers became concerned about liability. "The Illustrated Guide to Home Chemistry Experiments" steps up to the plate with lessons on how to equip your home chemistry lab, master laboratory skills, and work safely in your lab.The bulk of this book consists of 17 hands-on chapters that include multiple laboratory sessions on the following topics: Separating Mixtures; Solubility and Solutions; Colligative Properties of Solutions; Introduction to Chemical Reactions and Stoichiometry; Reduction-Oxidation (Redox) Reactions; Acid-Base Chemistry; Chemical Kinetics; Chemical Equilibrium and Le Chatelier's Principle; Gas Chemistry; Thermochemistry and Calorimetry; Electrochemistry; Photochemistry; Colloids and Suspensions; Qualitative Analysis; Quantitative Analysis; Synthesis of Useful Compounds; and Forensic Chemistry. With plenty of full-color illustrations and photos, Illustrated Guide to Home Chemistry Experiments offers introductory level sessions suitable for a middle school or first-year high school chemistry laboratory course, and more advanced sessions suitable for students who intend to take the College Board Advanced Placement (AP) Chemistry exam. A student who completes all of the laboratories in this book will have done the equivalent of two full years of high school chemistry lab work or a first-year college general chemistry laboratory course. This hands-on introduction to real chemistry - using real equipment, real chemicals, and real quantitative experiments - is ideal for the many thousands of young people and adults who want to experience the magic of chemistry.

The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing biomedical scientists today. It draws together essential basic science, with insights into laboratory practice, to show how an understanding of the biology of disease is linked to analytical approaches that lead to diagnosis. The series reviews the full range of disciplines to which a biomedical scientist may be exposed - from microbiology, to cytopathology, to transfusion science. The third edition of Biomedical Science Practice gives a comprehensive overview of key laboratory techniques and professional practial skills, with which students will need to be familiar to be successful in a professional biomedical enviroment.The text discusses a broad range of professional skills and concepts, such as health and safety considerations, personal development, and communication and confidentiality. The text also explores key experimental and analytical approaches which form the basis of the investigation and diagnosis of clinical conditions. Each chapter is supported with engaging clinical case studies, written to emphasize the link between theory and practice, and a set of end-of-chapter questions, which encourages students to test their knowledge and stretch their understanding. The third edition is available for students and institutions to purchase in a variety of formats and is supported by online resources. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks Online student resources supporting the book include: Answers to case study and self-check questions Multiple choice questions An interactive Digital Microscope, encouraging the exploration of tissue samples Video podcasts including interviews with practicing biomedical scientists, and 'in the lab' footage showing biomedical science in practice Online lecturer resources supporting the book include: Figures from the book, available to download

Focusing on the two seventeenth-century pioneers of microscopic discovery, the Dutchmen Jan Swammerdam and Antoni van Leeuwenhoek, the author demonstrates that their uneasiness with their social circumstances spurred their discoveries. Ruestow argues that while aspects of Dutch culture impeded serious research with the microscope, the contemporary culture shaped how Swammerdam and Leeuwenhoek responded to what they saw through the lens. For those interested in the history of science, this book considers the impact of institutionalization on microscopic research, and dissects the cultural, social and emotional circumstances that shaped early microscopic discovery.

As careers in science have become increasingly demanding, they require much more than a keen scientific mind and practical ability. If you are considering a career in research, have already embarked on your career and want to succeed, are uncertain which route to take or advise, train or supervise scientists, this book offers some helpful advice. Nancy Rothwell, a senior scientist with extensive experience training scientists and communicating with the public, covers topics ranging from choosing a PhD or postdoctoral position, successful interviews and preparing your cv to managing your supervisor; how to give successful talks, publish high quality papers and become known within your field. Broader aspects of science which are so important today are also covered, including ethics and fraud, intellectual property and exploitation and disseminating science to the public.