This volume analyzes both the theoretical and experimental aspects of neutron spectroscopy of solids, whereby complex crystals may be analyzed in relation to the theories of symmetry and neutron scattering near a structural or magnetic transition.

In its combination of an advanced teaching standpoint with an emphasis on new perspectives and recent advances in the study of liquids formed by simple molecules, Molecular Liquids: New Perspectives in Physics and Chemistry provides a clear, understandable guide through the complexities of the subject. A wide range of topics is covered in the areas of intermolecular forces, statistical mechanics, the microscopic dynamics of simple liquids, thermodynamics of solutions, nonequilibrium molecular dynamics, molecular models for transport and relaxation in fluids, liquid simulations, statistical band shape theories, conformational studies, fast-exchange dynamics, and hydrogen bonding. The experimental techniques covered include: neutron scattering, X-ray diffraction, IR, Raman, NMR, quasielastic neutron scattering, and high-precision, time-resolved coherent Raman spectroscopy.

Introducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, this unique, interdisciplinary reference explains the application of three-dimensional structural information in the design of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase presents recent results on the high-resolution three-dimensional structure of the catalytic core domain of HIV-1 integrase as a foundation for divergent combination therapy focuses on structure-based design strategies for uncovering receptor antagonists to treat inflammatory diseases demonstrates a systematic approach to the design of inhibitory compounds in cancer treatment reviews current knowledge on the Interleukin-1 (IL-1) system and progress in the development of IL-1 modulators describes the influence of structure-based methods in designing capsid-binding inhibitors for relief of the common cold and much more!

This book gives an up-to-date introduction to the structure, physical properties and applications of quasicrystalline alloys. It covers quasiperiodic tilings and the determination and modelling of the atomic structure of quasicrystals. The electronic properties, determined from measurements of the partial electronic density of states and the calculation of the electronic structure, play a key role in this introduction, as does an extensive discussion of the determination and simulation of the atomic dynamics. For the application of these aperiodic crystals, defects are a critical issue. Thus the book also presents a detailed treatement of the study of defects in quasicrystals by high resolution electron microscopy and ion channeling, as well as computer simulations of defects and fracture in decorated tilings.

The work focuses on recent developments of the rapidly evolving field of Non-conventional Liquid Crystals. After a concise introduction it discusses the most promising research such as biosensing, elastomers, polymer films , photoresponsive properties and energy harvesting. Besides future applications it discusses as well potential frontiers in LC science and technology.

This textbook presents an extensive manual of crystallography, including geometric crystallography, crystallochemistry, and crystallophysics. Illustrated with a wealth of figures and diagrams, it offers a thorough introduction to crystals for undergraduate and graduate students interested in learning the essentials and advanced concepts of crystallography. The book begins with basic concepts such as the geometry, morphology and symmetry of lattices, allowing readers to approach the subject from a mathematical point of view, abstracting it from its material content. In turn, the second part focuses on crystallochemistry and explains the differences between ideal and real crystals, and between static and dynamic ones. The third part of the textbook concerns crystallophysics and addresses the electrical, magnetic, mechanical, elastic and optical properties of crystals, as well as the fundamental laws and methods of X-ray diffraction.

1. The ninth International Summer School on Crystal Growth. ISSCG IX A complete theory of crystal growth establishes the full dependence of crystal size, shape and structure on external parameters like temperature, pressure, composition, purity, growth rate and stirring of the mother phase, implicitly establishing how the corresponding fields vary in space and time. Such a theory does not exist, however. Therefore equipment to grow crystals is developed on the basis of partial knowledge. Skill, experience and creativity still are of central importance for the success o~ a crystal growth system. In this book we collected contributions from the teachers of the ninth International Summer School on Crystal Growth ISSCG IX, held 11-16 june 1995 at Papendal, the national sports centre of the Netherlands. These contributions were used during the lectures. The authors have tried to present their work in such a way that only basic physical knowledge is required to understand the papers. The book can be used as an introduction to various important sub disciplines of the science and technology of crystal growth. Since, however the information content considerably exceeds a lecture note level and touches the present limits of understanding, it is an up to date handbook as well.

The concept of reciprocal space is over 100 years old, and has been of particular use by crystallographers in order to understand the patterns of spots when x-rays are diffracted by crystals. However, it has a much more general use, especially in the physics of the solid state. In order to understand what it is, how to construct it and how to make use of it, it is first necessary to start with the so-called real or direct space and then show how reciprocal space is related to it. Real space describes the objects we see around us, especially with regards to crystals, their physical shapes and symmetries and the arrangements of atoms within: the so-called crystal structure. Reciprocal space on the other hand deals with the crystals as seen through their diffraction images. Indeed, crystallographers are accustomed to working backwards from the diffraction images to the crystal structures, which we call crystal structure solution. In solid state physics, one usually works the other way, starting with reciprocal space to explain various solid-state properties, such as thermal and electrical phenomena. In this book, I start with the crystallographer's point of view of real and reciprocal space and then proceed to develop this in a form suitable for physics applications. Note that while for the crystallographer reciprocal space is a handy means of dealing with diffraction, for the solid-state physicist it is thought of as a way to describe the formation and motion of waves, in which case the physicist thinks of reciprocal space in terms of momentum or wave-vector k-space. This is because, for periodic structures, a characteristic of normal crystals, elementary quantum excitations, e.g. phonons and electrons, can be described both as particles and waves. The treatment given here, will be by necessity brief, but I would hope that this will suffice to lead the reader to build upon the concepts described. I have tried to write this book in a suitable form for both undergraduate and graduate students of what today we call "condensed matter physics."

This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems.

The bond valence model, a description of acid-base bonding, is widely used for analysing and modelling the structures and properties of solids and liquids. Unlike other models of inorganic chemical bonding, the bond valence model is simple, intuitive, and predictive, and is accessible to anyone with a pocket calculator and a secondary school command of chemistry and physics. This new edition of 'The Chemical Bond in Inorganic Chemistry: The Bond Valence Model' shows how chemical properties arise naturally from the conflict between the constraints of chemistry and those of three-dimensional space. The book derives the rules of the bond valence model, as well as those of the traditional covalent, ionic and popular VSEPR models, by identifying the chemical bond with the electrostatic flux linking the bonded atoms. Most of the new edition is devoted to showing how to apply these ideas to real materials including crystals, liquids, glasses and surfaces. The work includes detailed examples of applications, and the final chapter explores the relationship between the flux and quantum theories of the bond.

Knowledge of the microscopic structure of biological systems is the key to understanding their physiological properties. Most of what we now know about this subject has been generated by techniques that produce images of the materials of interest, one way or another, and there is every reason to believe that the impact of these techniques on the biological sciences will be every bit as important in the future as they are today. Thus the 21st century biologist needs to understand how microscopic imaging techniques work, as it is likely that sooner or later he or she will have to use one or another of them, or will otherwise become dependent on the information that they provide. The objective of this textbook is to introduce its readers to the many techniques now available for imaging biological materials, e.g. crystallography, optical microscopy and electron microscopy, at a level that will enable them to use them effectively to do research. Since all of these experimental methods are best understood in terms of Fourier transformations, this book explains the relevant concepts from this branch of mathematics, and then illustrates their elegance and power by applying them to each of the techniques presented. The book is derived from a one-term course in structural biology that the author gave for many years at Yale. It is intended for students interested either in doing structural research themselves, or in exploiting structural information produced by others. Over the years, the course was taken successfully by advanced undergraduates and by graduate students. Scientists interested in entering the structural biology field later in their careers may also find it useful.

Volume IA Handbook of Crystal Growth, 2nd Edition (Fundamentals: Thermodynamics and Kinetics) Volume IA addresses the present status of crystal growth science, and provides scientific tools for the following volumes: Volume II (Bulk Crystal Growth) and III (Thin Film Growth and Epitaxy). Volume IA highlights thermodynamics and kinetics. After historical introduction of the crystal growth, phase equilibria, defect thermodynamics, stoichiometry, and shape of crystal and structure of melt are described. Then, the most fundamental and basic aspects of crystal growth are presented, along with the theories of nucleation and growth kinetics. In addition, the simulations of crystal growth by Monte Carlo, ab initio-based approach and colloidal assembly are thoroughly investigated. Volume IB Handbook of Crystal Growth, 2nd Edition (Fundamentals: Transport and Stability) Volume IB discusses pattern formation, a typical problem in crystal growth. In addition, an introduction to morphological stability is given and the phase-field model is explained with comparison to experiments. The field of nanocrystal growth is rapidly expanding and here the growth from vapor is presented as an example. For the advancement of life science, the crystal growth of protein and other biological molecules is indispensable and biological crystallization in nature gives many hints for their crystal growth. Another subject discussed is pharmaceutical crystal growth. To understand the crystal growth, in situ observation is extremely powerful. The observation techniques are demonstrated.

Molecular chirality is one of the fundamental aspects of chemistry. Chirality properties of molecules have implications in a wide variety of subjects, ranging from the basic quantum mechanical properties of simple of a few atoms to molecular optical activity, asymmetric synthesis, systems and the folding pattern of proteins. Chirality, in both the geometrical and the topological sense, has also been the subject of investigations in various branches of mathematics. In particular, new developments in a branch of topology, called knot theory, as well as in various branches of discrete mathematics, have led to a novel perspective on the topological aspects of molecular chirality. Some of the mathematical advances have already found applications to the interpretation of new concepts in theoretical chemistry and mathematical chemistry, as well as to novel synthetic approaches leading to new molecules of exceptional structural properties. Some of the new developments in molecular chirality have been truly fundamental to the theoretical understanding and to the actual practice of many aspects of chemistry. The progress in this field has been very rapid, even accelerating in recent years, and a review appears more than justified. This book offers a selection of subjects covering some of the latest developments. Our primary aim is to clarify some of the basic concepts that are the most prone to misinterpretation and to provide brief introductions to some of those subjects that are expected to have further, important contributions to our understanding of molecular properties and chemical reactivity.

Vol 2A: Basic Technologies Handbook of Crystal Growth, Second Edition Volume IIA (Basic Technologies) presents basic growth technologies and modern crystal cutting methods. Particularly, the methodical fundamentals and development of technology in the field of bulk crystallization on both industrial and research scales are explored. After an introductory chapter on the formation of minerals, ruling historically the basic crystal formation parameters, advanced basic technologies from melt, solution, and vapour being applied for research and production of the today most important materials, like silicon, semiconductor compounds and oxides are presented in detail. The interdisciplinary and general importance of crystal growth for human live are illustrated. Vol 2B: Growth Mechanisms and Dynamics Handbook of Crystal Growth, Second Edition Volume IIB (Growth Mechanisms and Dynamics) deals with characteristic mechanisms and dynamics accompanying each bulk crystal growth method discussed in Volume IIA. Before the atoms or molecules pass over from a position in the fluid medium (gas, melt or solution) to their place in the crystalline face they must be transported in the fluid over macroscopic distances by diffusion, buoyancy-driven convection, surface-tension-driven convection, and forced convection (rotation, acceleration, vibration, magnetic mixing). Further, the heat of fusion and the part carried by the species on their way to the crystal by conductive and convective transport must be dissipated in the solid phase by well-organized thermal conduction and radiation to maintain a stable propagating interface. Additionally, segregation and capillary phenomena play a decisional role for chemical composition and crystal shaping, respectively. Today, the increase of high-quality crystal yield, its size enlargement and reproducibility are imperative conditions to match the strong economy.

Volume IIIA Basic Techniques Handbook of Crystal Growth, Second Edition Volume IIIA (Basic Techniques), edited by chemical and biological engineering expert Thomas F. Kuech, presents the underpinning science and technology associated with epitaxial growth as well as highlighting many of the chief and burgeoning areas for epitaxial growth. Volume IIIA focuses on major growth techniques which are used both in the scientific investigation of crystal growth processes and commercial development of advanced epitaxial structures. Techniques based on vacuum deposition, vapor phase epitaxy, and liquid and solid phase epitaxy are presented along with new techniques for the development of three-dimensional nano-and micro-structures. Volume IIIB Materials, Processes, and Technology Handbook of Crystal Growth, Second Edition Volume IIIB (Materials, Processes, and Technology), edited by chemical and biological engineering expert Thomas F. Kuech, describes both specific techniques for epitaxial growth as well as an array of materials-specific growth processes. The volume begins by presenting variations on epitaxial growth process where the kinetic processes are used to develop new types of materials at low temperatures. Optical and physical characterizations of epitaxial films are discussed for both in situ and exit to characterization of epitaxial materials. The remainder of the volume presents both the epitaxial growth processes associated with key technology materials as well as unique structures such as monolayer and two dimensional materials.

A large range of symmetries in art is presented through clear and aesthetically outstanding examples of historical ornaments. Compendious comments illustrate the selected photographic material by addressing the interested and specialist reader alike. Contents: Introduction Fundamental categories The convenient start: Plane groups of symmetry Intertwined patterns: Layer groups of symmetry Two-colored periodic ornamentation Polychromatic patterns Beyond 2D groups: Hypersymmetry, superstructures, two symmetries in one pattern, the "order-disorder" patterns, homothety and similarity, inversion and nonlinear patterns Quasiperiodic patterns Fractals and fractal character Style and symmetry - symmetry and style References Index

"Highlights in Mineralogical Crystallography" presents a collection of review articles with the common topic: structural properties of minerals and synthetic analogues. It is a valuable resource for mineralogists, materials scientists, crystallographers, and earth scientists. This book includes: An introduction to the RRUFF database for structural, spectroscopic, and chemical mineral identification. A systematic evaluation of structural complexity of minerals. ab initio computer modelling of mineral surfaces. Natural quasicrystals of meteoritic origin. The potential role of terrestrial ringwoodite on the water content of the Earth's mantle. Structural characterization of nanocrystalline bio-related minerals by electron-diffraction tomography. The uniqueness of mayenite-type compounds as minerals and high-tech ceramics.

Crystallography is an interdisciplinary science covering a wide area, from biology to earth sciences, mathematics and materials science. Its role is growing, owing to the contribution crystallography can offer to the understanding of such diverse fields as biological structures, high-temperature superconductors, mineral properties, and phase transitions. The book describes both the theoretical bases and applications of different areas interacting with crystallography. As with the first and second editions, it is organized as a collection of chapters written by recognized specialists, with all contributions being harmonized into a unified whole. The main text is devoted to the presentation of basics; the appendices deal with specialist aspects. In this third edition topics have been updated so as to document the present state of the art: emphasis is placed upon areas of current research.
To facilitate learning and make teaching more effective, new illustrations have been introduced. As with the second edition, a software package is included via the book's OUP web site: modern graphics will help users to better understand the basics of this science via three-dimensional images, simulation of experiments, and exercises.

Optical fibres have for almost three decades been fabricated from solid glass. It was, therefore, a radical change that took place, when researchers in the late 90s started to fabricate hair-thin optical fibres with numerous microscopic air holes running along the length of the fibres. These microstructured fibres did not only mark the introduction of tailored materials with unique spectral properties in fibre optics, but it also opened the perspective of the applicability of photonic bandgap materials at optical wavelengths. In this respect, a completely new guiding mechanism was demonstrated, and a revolution in fibre optics had started. Photonic Crystal Fibres describes the fundamental properties of these new optical waveguides, outlines how they are fabricated, and how they are treated from a theoretical and numerical point of view. A detailed description of the different classes of photonic crystal fibres is given, and a spectrum of different applications and new fibre types are presented. Photonic Crystal Fibres describes the fundamental properties of the optical waveguides known under the terms of photonic crystal fibres, microstructured fibres, or holey fibres. treated from a theoretical and numerical point of view. The book presents a detailed description of the different classes of photonic crystal and photonic bandgap fibres, and it broadens out a spectrum of novel applications and new fibre types.