Associates the application of coating technology for improving machining characteristics of difficult-to-cut materials Elaborates on the effect of coating architecture on the output machining parameters Explores the performance of coated cutting tools Discusses advanced coating systems and their application Includes industrial case studies and practical implementations where coatings were applied for the machining of difficult-to-cut materials

1) Aids professionals in meeting an increasing demand for more sustainable materials which are biodegradable, as nanomaterials meet these criteria 2) Monitors the impact of organic nanofillers in promoting polymer circular economy 3) Discusses computational studies on the effect of nanofillers on polymer matrices 4) Looks at properties of nanofillers including the mechanical, thermal, electrical, optical, and magnetic properties

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as heart disease, asthma, and diabetes. As the peak begins to slow in many countries, the death rates remain high amidst justified fears of a second wave. A rapid worldwide mobilization has begun to identify effective treatments and develop vaccines. This new volume will increase readers' understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss the effects of the virus in cases of co-morbidities, new treatment approaches, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers.

• Explores novel membrane materials and systems from preparation methods, materials selection, and their application in monitoring, fouling control, and performance enhancement. • Examines the mechanism of fouling prevention and cleaning in various electrically conductive materials. • Evaluates the scalability of antifouling materials and coatings, as well as electrically enhanced processes for monitoring and control in membrane separation technology • Assesses advantages and limitations of applying electrically conductive membrane systems to fouling control for specific water treatment applications. • Provides a critical review of scientific literature in the specialized area of electrical conductive materials and systems for membrane technology.

Mathematical Approaches to Liver Transplantation provides mathematical approaches to the optimization of liver graft distribution. Through mathematical and computational methods, several aspects related to organ allocation are tackled, with possible solutions presented. The book discusses topics such as patient selection for liver transplantation, transplantation procedures, dynamics of organs waiting list, improvement on grafts allocation, live donors and MELD scale. The content focuses on liver transplantation, however the mathematical approaches presented can be successfully replicated to different organs. This book is a valuable source for mathematical biologists, bioinformaticians, and several members of biomedical field who are involved in decision-making related to organs transplantation.

"Examines all known industrial processes using shape selective zeolites. Second Edition contains new, up-to-date information on the specific features that make zeolites shape selective, the role shape selective catalysis can play providing environmentally clean fuels, 12-membered oxygen ring systems, mesopore systems, and more."

This book covers liquid chromatography, gas chromatography and capillary electrophoresis, the three main separation techniques lately available, applied to key omic sciences, such as genomics, proteomics, metabolomics and foodomics. The fundamentals of each technique are not covered herein. Instead, the recent advances in such techniques are presented focusing on the application to omics analyses and unique aspects in each case. This volume intends to offer wide ranging options available to researchers on omics sciences, and how to integrate them in order to achieve the comprehension of a biological system as a whole. Omic sciences have been of ultimate importance to comprehend the complex biochemical reactions and related events that occurs upon a biological system. The classical central dogma of molecular biology, which states that genetic information flows unidirectionally from DNA to RNA and then to proteins, has been gradually replaced by the systems biology approach. This book presents a multidisciplinary approach that explains the biological system as a whole, where the entire organism is influenced by a variety of internal events as well as by the environment, showing that each level of the biological information flux may influence the previous or the subsequent one.

Features Introduces the physics of accelerators, lasers, and plasma in tandem with the industrial methodology of inventiveness. Outlines a path from idea to practical implementation of scientific and technological innovation. Contains more than 380 illustrations and numerous end-of-chapter exercises.

• Covers all aspects of why CBRN studies should be integrated into police education. • Provides guidance on teaching aspects of police education and practical information on scene sampling and chain of custody principles. • The first book to focus on why police need CBRN training to act effectively as first responders to incidents in the community.

Features Provides a unique, new approach to understanding quantum mechanics. Uses basic concepts and mathematical methods accessible at the undergraduate level. Presents applications outside physics, including a newly devised and original model of cell division that shows how cancer-cell population explosions occur.

Describes extensively the design and microfabrication of nanosensors based on nanotechnological tools. Provides a wide range of bioplatforms based on e.g., carbon nanostructures and Describes extensively a large number of application as a part of Nanomaterial based biosensors.

Metal-Air Batteries: Principles, Progress, and Perspectives covers the entire spectrum of metal-air batteries, their working principles, recent advancement, and future perspectives. Leading international researchers address materials design, electrochemistry, and architectural aspects. The fundamentals of metal-air materials for cathode and anode, their synthetic approaches, chemistries to modify their properties to provide high energy and power densities, along with long life and stable electrochemical characteristics are detailed. Key Features: Covers materials, chemistry, and technologies for metal-air batteries. Reviews state-of-the-art progress and challenges in metal-air batteries Provides fundamentals of the electrochemical behavior of various metal-air batteries. Offers insight into tuning the properties of materials to make them suitable for metal-air batteries. Provides new direction and a better understanding to scientists, researchers, and students working in diverse fields. This is a unique offering and a valuable resource for a wide range of readers including those in academia and industries worldwide.

This book is the first comprehensive overview of the emerging field of cuffless blood pressure monitoring. Increasing clinical evidence proves that longitudinal measurements of blood pressure allow for earlier detection and better management of multiple medical conditions and for superior prediction of cardiovascular events. Unfortunately, today's clinical and industry standards for blood pressure monitoring still require the inflation of a pneumatic cuff around a limb each time a measurement is taken. Over the last decades clinicians, scientists and device manufacturers have explored the feasibility of technologies that reduce or even completely eliminate the need of cuffs, initiating the era of cuffless blood pressure monitoring. Among the existing literature, this book is intended to be a practical guide to navigate across this emerging field. The chapters of the handbook have been elaborated by experts and key opinion leaders in the domain, and will guide the reader along the clinical, scientific, technical, and regulatory aspects of cuffless blood pressure monitoring.

Introduction to Modeling in Physiology and Medicine, Second Edition, develops a clear understanding of the fundamental principles of good modeling methodology. Sections show how to create valid mathematical models that are fit for a range of purposes. These models are supported by detailed explanation, extensive case studies, examples and applications. This updated edition includes clearer guidance on the mathematical prerequisites needed to achieve the maximum benefit from the material, a greater detail regarding basic approaches to modeling, and discussions on non-linear and stochastic modeling. The range of case study material has been substantially extended, with examples drawn from recent research experience. Key examples include a cellular model of insulin secretion and its extension to the whole-body level, a model of insulin action during a meal/oral glucose tolerance test, a large-scale simulation model of type 1 diabetes and its use in in silico clinical trials and drug trials.

Features Contains discussions of the basic principles of quantum optics and its importance to lasers, quantum information, and quantum computation. Provides references and a further reading list to additional scientific literature so that readers can use the book as a starting point to then follow up with a more advanced treatment of the topics covered. Requires only a basic background in undergraduate electrodynamics, quantum mechanics, and statistical mechanics.

Key Features: Describes feedstock evaluation and the effects of elemental, chemical and fractional composition. Details reactor types and bed types. Explores the process options and parameters involved. Assesses coke formation and additives. Considers next generation processes and developments.

Features Provides a unique, new approach to understanding quantum mechanics. Uses basic concepts and mathematical methods accessible at the undergraduate level. Presents applications outside physics, including a newly devised and original model of cell division that shows how cancer-cell population explosions occur.

Owing to their high-power density, long life and environmental compatibility, supercapacitors are emerging as one of the promising storage technologies but with challenges around energy and power requirements for specific applications. This book focusses on supercapacitors including details on classification, charge storage mechanisms, related kinetics, and thermodynamics. Materials used as electrodes, electrolytes and separators, and procedures followed, characterization methods and modeling are covered along with emphasis on related applications. Features: Provides an in-depth look at supercapacitors, including their working concepts, and design. Reviews detailed explanation of various characterization and modeling techniques. Give special focus to the application of supercapacitors in major areas of environmental as well as social importance. Covers Cyclic Voltammetry, Charging-Discharging Curves, and Electrochemical Impedance Spectroscopy as characterization techniques. Includes a detailed chapter on historical perspectives on evolution of supercapacitors. This book aims at researchers, and graduate students in materials science and engineering, nanotechnology, chemistry in batteries, and physics.

Reports on waste valorization in the winemaking industry and converting the waste into more useful products including oils, antioxidants and other valuable materials. Explores research which contributes to environmental sustainability and circular economy in the winemaking industry. Describes other ways to reduce the ecological footprint of the wine industry such as using less fertilizer, more benign pesticides and reduction of water footprint. Proposes options for a potential wine waste biorefining. Reviews alternative uses of agro-industrial wine wastes as sources of additives for the food, cosmetic and pharmaceutical industries.

Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels.

Translational Sports Medicine covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. This title is an indispensable tool in grant writing and funding efforts with its practical, straightforward approach that will help aspiring investigators navigate challenging considerations in study design and implementation. It provides valuable discussions of the critical appraisal of published studies in translational sports medicine, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or sports medicine clinician who has ever had a good clinical idea but not the knowledge of how to test it. Readers will come to fully understand important concepts, including case-control study, prospective cohort study, randomized trial and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in translational sports medicine, and know what is needed in collaboration.

The last documented sighting of the Ivory-billed Woodpecker--one of the rarest and most intriguing animals in the world--was noted over 50 years ago. Long thought to be extinct, the 2005 announcement of a sighting in Arkansas sparked tremendous enthusiasm and hope that this species could yet be saved. But the subsequent failure of a massive search to relocate Ivorybills in Arkansas made hope for the species' revival short-lived.
Here, noted ornithologist Geoffrey Hill tells the story of how he and two of his colleagues stumbled upon what may be a breeding population of Ivory-billed Woodpeckers in the swamps of northern Florida. He relates their laborious attempts to document irrefutable evidence for the existence of this shy, elusive bird following the failure of a much larger research team to definitively prove the bird's existence.
Hill tells of his travails both in and out of the vast swamp wilderness, pulling back the curtain to reveal the little-seen political maneuvering that is part of all modern science. He explains how he and his group decided who to exclude or include as their findings came in, and why they felt the need to keep their search a secret. Hill returns repeatedly to how expectations can guide observations, and how tempting it is to oversell evidence in the face of the struggle between an overwhelming desire to find the bird and the need to retain integrity and objectivity.
Written like a good detective story, Ivorybill Hunters also delves into the science behind the rediscovery of a species, explaining how professional ornithologists follow up on a sight record of a rare bird, and how this differs from the public's perception of how scientistsactually work. Hill notes the growing role of amateurs in documenting bird activity and discusses how the community of birders and nature lovers can see, enjoy, and help preserve these birds.
Ivorybill Hunters will prove a fascinating read for those with an interest in natural history, adventure, environmental conservation, and science, as well as the more than forty-six million Americans who now call themselves birdwatchers.

1. Focuses on these newly available antibacterial, their mechanism of actions, resistance, and spectrum of activities 2. Useful for Biologists, Bioengineers, Biochemist, Biotechnologists, Microbiologists, Food technologists, Enzymologists 3. Discusses new unexploited targets and strategies for the next generation of antimicrobial drugs for combating the drug resistance and emerging pathogens

Features Surveys of the systems approach to analysing and understanding multifaceted, complex problems in astrobiology, written by two scientists who also have engineering backgrounds. Systems applications to areas important to astrobiology, such as chemical evolution, prebiotic chemistry, geochemical/geophysical settings conducive to emergence of life, robotic space exploration, and much more. Wide appeal for all readers interested in the origin and occurrence of life in our Solar System and beyond.

Reports on waste valorization in the winemaking industry and converting the waste into more useful products including oils, antioxidants and other valuable materials. Explores research which contributes to environmental sustainability and circular economy in the winemaking industry. Describes other ways to reduce the ecological footprint of the wine industry such as using less fertilizer, more benign pesticides and reduction of water footprint. Proposes options for a potential wine waste biorefining. Reviews alternative uses of agro-industrial wine wastes as sources of additives for the food, cosmetic and pharmaceutical industries.