Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource.

Cancer is one of the most devastating diseases in the world today, but early prevention remains the key to controlling it. Charles H. Chen shows that through a strict regime of diet, exercise, and other healthy lifestyle changes, you can increase your chances of keeping cancer from your doorstep.

Diagnosed with colon cancer in 1998, Chen decided to tackle the disease head on and was determined to learn the causes of cancer, the treatments, and prevention methods. Chen brings a unique perspective to this subject as both a medical doctor and a cancer survivor, breaking down the various aspects of this worldwide epidemic. Practical and concise, "An Intimate Relationship" covers topics such as: Screenings for men and women Benefits of early diagnosis Treatment options Prevention and healthy lifestyle choices

As a gynecologist, Chen also focuses on women's cancer issues, including breast cancer and hormone replacement therapy. He also provides tips to help you achieve good health through the consumption of organic foods, antioxidants, and nutritional supplements.

Don't become a statistic-increase your chances of avoiding cancer and improve your overall health with "An Intimate Relationship."

Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug resistance occurs during chemotherapy. In addition, users will find the current therapeutic strategies used by clinicians in their practice in treating colorectal cancer. The combination of conventional anticancer drugs with chemotherapy-sensitizing agents plays a pivotal role in improving the outcome of colorectal cancer patients, in particular those with drug-resistant cancer cells. From a clinical point-of-view, the content of this book provides clinicians with updated therapeutic strategies for a better choice of drugs for drug-resistant colorectal cancer patients. It will be a valuable source for cancer researchers, oncologists and several members of biomedical field who are dedicated to better treat patients with colorectal cancer.

This book is partly based on research funded by Wereld Kanker Onderzoek Fonds based in the Netherlands and administered by the World Cancer Research Fund International grant program. Every year half a million of people worldwide are diagnosed with bladder cancer. With the recent zeitgeist of the self-empowered, intelligent patient who wishes to be well-informed, many cancer patients do not solely want to rely on decisions taken by medical practitioners, but actively participate in the journey from sickness to health or disease. While no books about the relationship between diet and bladder cancer currently exist, the poor quality of the existing information about the relationship between diet and health is shocking. Much of the information is exaggerated, not evidence-based, misleading and sometimes even incorrect. Dr. Maurice Zeegers, one of the world leading bladder cancer epidemiologists, and his co-authors set the record straight with this book on Diet and Fighting Bladder Cancer. Their aim is to provide purely evidence-based information about the relationship between diet and bladder cancer. The primary audience is bladder cancer patients who wish to be well-informed, although clinicians and healthcare workers may also find the book an interesting read. The book gives an honest reflection on what scientists know, but also what they don't yet know about how diet contributes to all stages of this important disease. Although science-based, the book is written in an easy-to-read format, illustrated with practical recipes.

Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells from patient referral to post-therapy management in a concise and practical format. Providing clinical guidance on the implementation and management of CAR T-cell therapy, this clinical resource keeps you up-to-date on the latest developments in this rapidly evolving area. Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging therapy, post-CAR monitoring, and multidisciplinary approaches to supportive care. Includes key topics on associated toxicities such as predictive biomarkers, infections, and multidisciplinary approaches to supportive care. Presents current knowledge on FDA approved CAR T-cell products as well as developments on the horizon. Editors and authors represent leading investigators in academia and worldwide pioneers of CAR therapy.

Prognostic and Therapeutic Applications of RKIP in Cancer provides updated reviews on the chemistry, signaling, pre-clinical and clinical activities, and role of RKIP expression levels for diagnostics, prognosis and potential interventions. The development of novel compounds and conjugates that selectively induce RKIP expression in cancer open a novel era of new therapeutics and their potential in the treatment of highly resistant cancers and metastases. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students.

This book will contain a series of review articles that focus on retroviral models of human and animal cancers. Each article will be written by an expert in the field of retrovirology. The reviews will summarize current work on a particular retrovirus, with particular emphasis on the relevance of this research to human disease.