Between the two World Wars an illness that mainly affects adults over fifty years old became so prominent that it superseded both tuberculosis and syphilis in importance.
As Patrice Pinell shows, the effect of cancer in France before World War Two reached far beyond the question of its mortality rates. Pinell's socio-historical approach to the early developments in the fight against cancer describes how scientific, therapeutic, philanthropic, ethical, social, economics and political interest combined to transform medicine.

Early modern physicians and surgeons tried desperately to understand breast cancer, testing new medicines and radically improving operating techniques. In this study, the first of its kind, Kaartinen explores the emotional responses of patients and their families to the disease in the long eighteenth century.

This book presents original results on the leading edge of cancer research. Topics discussed include the emerging roles of the Sirtuin family in cancer; coping with pain in children with leukaemia; chemotherapy induced peripheral neurotoxicity; historical evolution of conservative surgery of breast cancer; peripheral neuropathies especially in cancer patients; the important pitfalls in the diagnosis of cancer in the oral cavity using 18F-FDG-PET-CT; anthracyclines and cardiotoxicity; current therapies and latest developments in cancer treatment; and the genetic and epigenetic changes in thyroid cancer.

This book presents original results on the leading edge of cancer research. Topics discussed include oral cancer cachexia; the immunological mechanisms of cachexia; research in gynaecologic oncology today; advances in cellular understanding of muscle wasting in cachexia; and next generation sequencing developments in cancer research by bioinformatics approaches.

Although many skin lesions are pigmented, Dermatoscopy of Non-pigmented Skin Tumors: Pink - Think - Blink addresses non-pigmented lesions, which may be more difficult to diagnose. It discusses dermatoscopy not only as a reliable tool for diagnosis, but also for the monitoring of treatment outcomes following topical therapy. The clinical diagnosis of non-pigmented skin lesions is one of the most challenging in the daily routine. To arrive at a correct diagnosis-or at least an adequate management plan-the clinician needs to collect many pieces of information and put them together like a puzzle. Illustrated with nearly 200 color clinical and dermatoscopic photographs, this book is an invaluable guide for clinicians striving to solve the diagnostic puzzle and correctly identify non-pigmented lesions.

This book is comprised of extensive reviews and instructional chapters that discuss the quality of life in several aspects of cancer. The first six chapters deal with conceptual issues relating to measuring quality of life in adult and pediatric populations with cancer. The next five chapters provide practical information on how to select quality-of-life measures, the statistical analysis of trials, economic evaluations to be considered, and some possible abuses of quality-of-life measures. Five chapters review the results of studies using selected quality-of-life measures and provide recent information on their performance. These are followed by three chapters dealing with specific issues relating to nausea and vomiting associated with cancer therapy. Three chapters are devoted to the problems of assessing and controlling pain in patients who have cancer. There are also two chapters that deal with the quality of life in palliative care. Effect of Cancer on Quality of Life is intended for all who have an interest in measuring the quality of life in patients with cancer. This includes investigators who are just entering the field and can benefit from instructions on how to conduct quality-of-life research, as well as those who are experienced in conducting this kind of research.

The complete mapping of the human genome, along with the development of sophisticated molecular technologies, has accelerated research on the relationship between nutrients and genes. This has led to compelling evidence garnered from epidemiological and experimental observations supporting the idea that the interaction between nutrients and genes is one of the most important mechanisms influencing carcinogenesis. Nutrient-Gene Interactions in Cancer brings together leading authorities in the field who provide an overview and look specifically at the mechanisms known to underlie each nutrient and gene interaction. The book examines the multi-functional relationship linking nutrition and cancer development, including the complex role nutrients have in modulating cancer growth via interactions with specific genes, and the emerging new strategy for cancer chemoprevention that is based on a deepened understanding of this relationship. The authors also provide freshly illuminating information on many well-known interactions. The first part of the book includes chapters on the basic elements of biology and pathobiology of gene-nutrient interactions with a focus on mechanisms and biomarkers. This is followed by chapters, which detail specific gene-nutrient interactions, offering numerous examples supported by recent investigations. The final chapter looks to the future, considering the potential for further investigation by outlining new perspectives in this rapidly growing area of medical science. While this work is especially valuable to science investigators, it will also be of great interest to clinicians who manage cancer patients, in that it presents useful tools that advance the clinical value of gene-nutrient interaction research in medical nutrition and oncology.

Collaborative Practice in Palliative Care explores how different professions work collaboratively across professional, institutional, social, and cultural boundaries to enhance palliative care. Analysing palliative care as an interaction between different professionals, clients, and carers, and the social context or community within which the interaction takes place, it is grounded in up-to-date evidence, includes global aspects of palliative care and cultural diversity as themes running throughout the book, and is replete with examples of good and innovative practice. Drawing on experiences from within traditional specialist palliative care settings like hospices and community palliative care services, as well as more generalist contexts of the general hospital and primary care, this practical text highlights the social or public health model of palliative care. Designed to support active learning, it includes features such as case studies, summaries, and pointers to other learning resources. This text is an important reference for all professionals engaged in palliative care, particularly those studying for post-qualification programmes in the area.

Describes the ways Vitamin C can inhibit, perturb or retard the growth and spread of cancer through changing the ways cancers respond to different doses and treatmentsSumarizes the results of clinical trialsOutlines therapeutical usesChapters by an international team of researchers.

Over the past ten years there has been a dramatic increase in new nursing roles and nurse-led clinics within oncology. This unique handbook is a comprehensive companion for nurses studying and practising at an advanced level in this emerging field. This text outlines and discusses roles, responsibilities and skills related to advanced practice in oncology nursing - including leadership, communication skills and prescribing - linking throughout to the implications for clinical practice. It then provides a step-by-step guide to setting up and developing nurse-led clinics, looking in more detail at clinics focusing on surgery, chemotherapy, radiotherapy, clinical trials and follow ups, and providing an in-depth case example of a clinic set up for adjuvant Herceptin use. Practical, relevant and underpinned by current legislation, Advanced Nursing Practice and Nurse-led Clinics in Oncology is an invaluable resource for oncology nurses.

Over the past ten years there has been a dramatic increase in new nursing roles and nurse-led clinics within oncology. This unique handbook is a comprehensive companion for nurses studying and practising at an advanced level in this emerging field. This text outlines and discusses roles, responsibilities and skills related to advanced practice in oncology nursing - including leadership, communication skills and prescribing - linking throughout to the implications for clinical practice. It then provides a step-by-step guide to setting up and developing nurse-led clinics, looking in more detail at clinics focusing on surgery, chemotherapy, radiotherapy, clinical trials and follow ups, and providing an in-depth case example of a clinic set up for adjuvant Herceptin use. Practical, relevant and underpinned by current legislation, Advanced Nursing Practice and Nurse-led Clinics in Oncology is an invaluable resource for oncology nurses.

At no time in U.S. history has there been a more effective challenge to medical expertise and authority than that mounted by the contemporary Laetrile movement. The efficacy of Laetrile has been debated for over twenty-five years, but despite vigorous opposition from the medical community, support for the purported cancer treatment continues to gro

This is the first all-encompassing textbook designed to support trainee clinical scientists in medical physics as they start work in a hospital setting whilst undertaking an academic master's course. Developed by practising physicists and experienced academics using their experience of teaching trainee medical physicists, this book provides an accessible introduction to the daily tasks that clinical scientists perform in the course of their work. It bridges the gap between theory and practice, making the book also suitable for advanced undergraduate and graduate students in other disciplines studying modules on medical physics, including those who are considering a career in medical physics through applying to the NHS Scientist Training Programme (STP). Features: Provides an accessible introduction to practical medical physics within a hospital environment Maps to the course content of the Scientist Training Programme in the NHS Acts as a complement to the academic books often recommended for medical physics courses

This book covers the complete gamut of neuroradiology cases, including normal anatomy, pitfalls, and artifacts across the brain and spine in a single volume, enriched with high-resolution images that support the interpretation of CT and MRI images of the brain, spine, head, and neck. It includes case studies commonly encountered in clinical practice, in addition to normal anatomy, that prepare the reader for the challenges in the clinical setting. Each case study discusses the clinical history, relevant imaging findings, differential diagnosis, and management, serving as a helpful read for trainee radiologists, neurophysicians, neurosurgeons, and CT/MRI technicians, along with physicians interested in medical imaging. Key Features Provides a succinct overview of normal variants with case studies structured into thematic chapters Serves as a basic accompaniment for radiology residents, fellows, practicing radiologists, neurophysicians, neurosurgeons, emergency medicine practitioners, trainee and practicing radiographers, and those studying for Board exams Highlights the relevance of artificial intelligence in clinical practice

This valuable self-help book for people affected by cancer, their loved ones and friends focuses on self-care when life hurts. It explores the impact of cancer and explains why the usual ways of coping may leave people stuck. The first book of its kind to focus on the scientifically based Acceptance and Commitment Therapy (ACT) approach, it helps people to find ways to cope with painful thoughts and feelings, and to rebuild a meaningful life despite the cancer. With an emphasis on value-based living the book illustrates skills such as mindfulness and the development of acceptance to help people affected by cancer to participate in a fuller life and gain a greater sense of well-being. It combines evidence-based practice with the experiences of people who are living with cancer in the form of numerous quotations throughout, as well as paper and pencil 'thought' exercises. Living Your Life with Cancer through Acceptance and Commitment Therapy helps people affected by cancer to feel more able to sit with the uncertainty of their future, show themselves kindness and compassion and to learn to be true to themselves, no matter what the cancer throws at them. It is also important reading for psychological therapists working in oncology.

Barbara Delinsky's 1998 bestseller, COAST ROAD, featured a heroine who was a breast cancer survivor. To this day, it is the book that generates more mail than any of her others. That fact, combined with Barbara's ongoing commitment to breast cancer research, led her to her first book of nonfiction. Not a medical book -- there is no discussion of the pros and cons of a particular treatment or hospital or doctor -- UPLIFT is rather a collection of hundreds of pieces of practical and inspiring tidbits collected from survivors and their on everything from what kind of deodorant to use during radiation treatment to the best kinds of exercise aftloved ones. Think of it as "The Girlfriends' Guide" to breast cancer, with hints on everything from what kind of deodorant to use during radiation treatment to the best kinds of exercise after a mastectomy to how to tell the person you're most afraid to tell that you have cancer.
And as timeless as ever, this newly revised edition of UPLIFT contains the latest and most up-to-the-minute medical information, as well as new stories from inspiring cancer survivors.

Stem cell research is one of the fascinating areas of contemporary biology, but, as with many expanding fields of scientific inquiry, research on stem cells raises scientific questions as rapidly as it generates discoveries. Research on stem cell treatment continues to advance knowledge about how an organism develops from a single cell and how healthy cells replace damaged cells in adult organisms. The most important potential application of human stem cells is the generation of cells and tissues that could be used for cell-based therapies, especially oncology. The Faculty of Medicine, Universitas Sumatera Utara, collaborated with the center of excellence and innovation (Pusat Unggulan Inovasi /PUI). The Stem Cell center of the Universitas Sumatera Utara (USU) organized an International Conference. The International Stem Cell and Oncology Conference (ISCOC) 2017 was a comprehensive academic conference in the field of stem cell and oncology research and also tropical medicine and related scientific topics. We expect Stem Cell Oncology will benefit academics and practitioners in the field of health sciences in Indonesia. This is an Open Access ebook, and can be found on www.taylorfrancis.com.

This second edition comes at a time of a paradigm shift in understanding of the molecular pathology and neuroscience of brain and spinal tumors of childhood and their mechanisms of growth within the developing brain. Excellent collaborative translational networks of researchers are starting to drive change in clinical practise through the need to test many ideas in trials and scientific initiatives. This text reflects the growing concern to understand the impact of the tumour and its treatment upon the full functioning of the child's developing brain and to integrate the judgments of the risks of acquiring brain damage with the risk of death and the consequences for the quality of life for those who survive. Information on the principles of treatment has been thoroughly updated. A chapter also records the extraordinary work done by advocates. All medical and allied professionals involved in any aspect of the clinical care of these patients will find this book an invaluable resource.

Recent global cancer statistical data has clearly indicated that prostate cancer is currently the second most frequently diagnosed cancer (at 15% of all male cancers) and globally the sixth leading cause of cancer death in males. This book is a summary of prostate cancer, covering its incidence, epidemiology, and current treatment options. It also serves as an up-to-date review of the status of currently available alternative and complementary medicines for treating prostate cancer, including various plant extracts, herbal formulations, natural products, yoga, acupuncture, Ayurveda, homeopathy, and Siddha medicines used in prostate cancer therapy.

Cell signaling is a field that studies how cells communicate to control basic activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a cellular level, an understanding that may have implications for developing new treatments. The current volume provides an overview of the field and how various cell biology techniques are used to better understand cancer on a cellular level. This easily accessible reference volume offers a comprehensive look at the field of cancer cell signaling. Edited by a researcher from Florida Atlantic University, Cancer Cell Signaling: Targeting Signaling Pathways Towards Therapeutic Approaches to Cancer" "is an authoritative and easy-to-use reference.

This book covers the complete gamut of neuroradiology cases, including normal anatomy, pitfalls, and artifacts across the brain and spine in a single volume, enriched with high-resolution images that support the interpretation of CT and MRI images of the brain, spine, head, and neck. It includes case studies commonly encountered in clinical practice, in addition to normal anatomy, that prepare the reader for the challenges in the clinical setting. Each case study discusses the clinical history, relevant imaging findings, differential diagnosis, and management, serving as a helpful read for trainee radiologists, neurophysicians, neurosurgeons, and CT/MRI technicians, along with physicians interested in medical imaging. Key Features Provides a succinct overview of normal variants with case studies structured into thematic chapters Serves as a basic accompaniment for radiology residents, fellows, practicing radiologists, neurophysicians, neurosurgeons, emergency medicine practitioners, trainee and practicing radiographers, and those studying for Board exams Highlights the relevance of artificial intelligence in clinical practice

This book addresses a wide range of topics, from the principles of evidence-based practice to the process and dissemination of research to unique considerations such as clinical trials, patenting, and health services research. The case for evidence-based practice and a collaborative research culture is made first, followed by a series of chapters walking the reader through the research process by way of the scientific method. One of the more unique aspects of the scope of this book is the inclusion of chapters relating to the dissemination of knowledge, manuscript publication, and how to build an academic research program. Each chapter focuses on introducing the reader to foundational principles, methodology, and terminology, and highlight case studies of radiation therapist research or experience that is relevant to provide contextual examples and inspiration to the reader.

Written by world authorities on the subject, this reference comprehensively covers every aspect of colorectal cancer. Addressing the molecular mechanisms, genetics, identification, and therapy of disease, this guide covers new pharmaceutical developments, current screening protocols, and modern methods of disease management by specialists at renowned institutions such as the Royal Marsden Hospital, the Memorial Sloan Kettering Cancer Center, and the Vanderbilt-Ingram Cancer Center.

Reflecting the increased importance of the collaborations between radiation oncology and informatics professionals, Informatics in Radiation Oncology discusses the benefits of applying informatics principles to the processes within radiotherapy. It explores how treatment and imaging information is represented, stored, and retrieved as well as how this information relates to other patient data. The book deepens your knowledge of current and emerging information technology and informatics principles applied to radiation oncology so that all the data gathered-from laboratory results to medical images-can be fully exploited to make treatments more effective and processes more efficient. After introducing the basics of informatics and its connection to radiation oncology, the book examines the process of healthcare delivery in radiation oncology, the challenges of managing images in radiotherapy, and the burgeoning field of radiogenomics. It then presents teaching, clinical trials, and research tools and describes open access clinical imaging archives in radiotherapy, techniques for maximizing information from multimodality imaging, and the roles of images in treatment planning. It also looks at how informatics can improve treatment planning, the safety and efficiency of delivery systems, image-guided patient positioning, and patient assessment. The book concludes with discussions on how outcomes modeling evaluates the effectiveness of treatments, how quality control informatics improves the reliability of processes, and how to perform quality assurance on the informatics tools. With contributions from a host of top international experts in radiation oncology, medical physics, and informatics, this book leads the way in moving the field forward. It encourages you to find new ways of applying informatics to radiation oncology and help your patients in their fight against cancer.