Reviews in Fluorescence 2009, the sixth volume of the book serial from Springer, serves as a comprehensive collection of current trends and emerging hot topics in the field of fluorescence and closely related disciplines. It summarizes the year's progress in fluorescence and its applications, with authoritative analytical reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of fluorescence. Reviews in Fluorescence offers an essential reference material for any lab working in the fluorescence field and related areas. All academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of fluorescence will find it an invaluable resource. Reviews in Fluorescence 2009 topics include: Hot electron-Induced Electrogenerated Chemiluminescence. Time-correlated, single-photon counting methods in endothelial cell mechanobiology. Origin of Tryptophan Fluorescence. Protein Folding, Unfolding and Aggregation Processes revealed by Rapid Sampling of Time-Domain Fluorescence.

The Advanced Study Institute on "Path Integrals and Their Applications in Quantum, Statistical, and Solid State Physics" was held at the University of Antwerpen (R.U.C.A.), July 17-30, 1977. The Institute was sponsored by NATO. Co-sponsors were: A.C.E.C. (Belgium), Agfa-Gevaert (Belgium), l'Air Li~uide BeIge (Belgium), Be1gonucleaire (Belgium), Bell Telephone Mfg. Co. (Belgium), Boelwerf (Belgium), Generale BankmaatschappiJ (Belgium), I.B.M. (Belgium), Kredietbank (Belgium), National Science Foundation (U.S.A.), Siemens (Belgium). A total of 100 lecturers and partici- pants attended the Institute. The development of path (or functional) integrals in relation to problems of stochastic nature dates back to the early 20's. At that time, Wiener succeeded in obtaining the fundamental solution of the diffusion e~uation using Einstein's joint probability of finding a Brownian particle in a succession of space intervals during a corresponding succession of time intervals. Dirac in the early 30's sowed the seeds of the path integral formulation of ~uantum mecha- nics. However, the major and decisive step in this direction was taken with Feynman's works in ~uantum and statistical physics, and quantum electrodynamicso The applications now extend to areas such as continuous mechanics, and recently functional integration methods have been employed by Edwards for the study of polymerized matter.

This thesis combines highly accurate optical spectroscopy data on the recently discovered iron-based high-temperature superconductors with an incisive theoretical analysis. Three outstanding results are reported: (1) The superconductivity-induced modification of the far-infrared conductivity of an iron arsenide with minimal chemical disorder is quantitatively described by means of a strong-coupling theory for spin fluctuation mediated Cooper pairing. The formalism developed in this thesis also describes prior spectroscopic data on more disordered compounds. (2) The same materials exhibit a sharp superconductivity-induced anomaly for photon energies around 2.5 eV, two orders of magnitude larger than the superconducting energy gap. The author provides a qualitative interpretation of this unprecedented observation, which is based on the multiband nature of the superconducting state. (3) The thesis also develops a comprehensive description of a superconducting, yet optically transparent iron chalcogenide compound. The author shows that this highly unusual behavior can be explained as a result of the nanoscopic coexistence of insulating and superconducting phases, and he uses a combination of two complementary experimental methods - scanning near-field optical microscopy and low-energy muon spin rotation - to directly image the phase coexistence and quantitatively determine the phase composition. These data have important implications for the interpretation of data from other experimental probes.

Elucidating Organic Reaction Mechanisms using photo-CIDNP Spectroscopy, by Martin Goez. Parahydrogen Induced Polarization by Homogeneous Catalysis: Theory and Applications, by Kerstin Munnemann et al. Improving NMR and MRI Sensitivity with Parahydrogen, by R. Mewis & Simon Duckett. The Solid-state Photo-CIDNP Effect, by Jorg Matysik et al. Parahydrogen-induced Polarization in Heterogeneous Catalytic Processes, by Igor Koptyug et al. Dynamic Nuclear Polarization Enhanced NMR Spectroscopy, by U. Akbey & H. Oschkinat. Photo-CIDNP NMR Spectroscopy of Amino Acids and Proteins, by Lars T. Kuhn."

The book is designed for end users in the field of digital imaging, who wish to update their skills and understanding with the latest techniques in image analysis. The book emphasizes the conceptual framework of image analysis and the effective use of image processing tools. It uses applications in a variety of fields to demonstrate and consolidate both specific and general concepts, and to build intuition, insight and understanding. Although the chapters are essentially self-contained they reference other chapters to form an integrated whole. Each chapter employs a pedagogical approach to ensure conceptual learning before introducing specific techniques and "tricks of the trade". The book concentrates on a number of current research applications, and will present a detailed approach to each while emphasizing the applicability of techniques to other problems. The field of topics is wide, ranging from compressive (non-uniform) sampling in MRI, through automated retinal vessel analysis to 3-D ultrasound imaging and more. The book is amply illustrated with figures and applicable medical images. The reader will learn the techniques which experts in the field are currently employing and testing to solve particular research problems, and how they may be applied to other problems.

The study of quantum disorder has generated considerable research activity in mathematics and physics over past 40 years. While single-particle models have been extensively studied at a rigorous mathematical level, little was known about systems of several interacting particles, let alone systems with positive spatial particle density. Creating a consistent theory of disorder in multi-particle quantum systems is an important and challenging problem that largely remains open. Multi-scale Analysis for Random Quantum Systems with Interaction presents the progress that had been recently achieved in this area. The main focus of the book is on a rigorous derivation of the multi-particle localization in a strong random external potential field. To make the presentation accessible to a wider audience, the authors restrict attention to a relatively simple tight-binding Anderson model on a cubic lattice Zd. This book includes the following cutting-edge features: an introduction to the state-of-the-art single-particle localization theory an extensive discussion of relevant technical aspects of the localization theory a thorough comparison of the multi-particle model with its single-particle counterpart a self-contained rigorous derivation of both spectral and dynamical localization in the multi-particle tight-binding Anderson model. Required mathematical background for the book includes a knowledge of functional calculus, spectral theory (essentially reduced to the case of finite matrices) and basic probability theory. This is an excellent text for a year-long graduate course or seminar in mathematical physics. It also can serve as a standard reference for specialists.

Helium Ion Microscopy: Principles and Applications describes the theory and discusses the practical details of why scanning microscopes using beams of light ions - such as the Helium Ion Microscope (HIM) - are destined to become the imaging tools of choice for the 21st century. Topics covered include the principles, operation, and performance of the Gaseous Field Ion Source (GFIS), and a comparison of the optics of ion and electron beam microscopes including their operating conditions, resolution, and signal-to-noise performance. The physical principles of Ion-Induced Secondary Electron (iSE) generation by ions are discussed, and an extensive database of iSE yields for many elements and compounds as a function of incident ion species and its energy is included. Beam damage and charging are frequently outcomes of ion beam irradiation, and techniques to minimize such problems are presented. In addition to imaging, ions beams can be used for the controlled deposition, or removal, of selected materials with nanometer precision. The techniques and conditions required for nanofabrication are discussed and demonstrated. Finally, the problem of performing chemical microanalysis with ion beams is considered. Low energy ions cannot generate X-ray emissions, so alternative techniques such as Rutherford Backscatter Imaging (RBI) or Secondary Ion Mass Spectrometry (SIMS) are examined.

A key experiment in biomedical research is monitoring the expression of different proteins in order to detect changes that occur in biological systems under different experimental conditions. The method that is most widely used is the Western blot analysis. While Western blot is a workhorse in laboratories studying protein expression and has several advantages, it also has a number of significant limitations. In particular, the method is semi-quantitative with limited dynamic range. Western blot focuses on a single protein per sample with only a small number of representative samples analyzed in an experiment. New quantitative tools have been needed for some time to at least supplement, & possibly replace, the Western blot. Mass spectrometric methods have begun to compete with Western blot for routine quantitative analyses of proteins. One of these methods is based on the tandem mass spectrometry technique of selected reaction monitoring (SRM), which is also called multiple reaction monitoring (MRM). Selected reaction monitoring is actually an older tandem mass spectrometry technique, first described in the late 70s, that is widely utilized in the quantitative analysis of small molecules like drugs & metabolites. The use of selected reaction monitoring for the quantitative analysis of proteins has a number of advantages. Most importantly, it is fundamentally quantitative with a wide dynamic range. The output of the analysis is a numerical result that can range over several orders of magnitude. Other advantages include sufficient specificity & sensitivity to detect low abundance proteins in complex mixtures. Finally, selected reaction monitoring can be multiplexed to allow the quantitative analysis of relatively large numbers of proteins in a single sample in a single experiment. This Brief will explain both the theoretical & experimental details of the selected reaction monitoring experiment as it is applied to proteins.

This book provides a concise survey of modern theoretical concepts of X-ray materials analysis. The principle features of the book are: basics of X-ray scattering, interaction between X-rays and matter and new theoretical concepts of X-ray scattering. The various X-ray techniques are considered in detail: high-resolution X-ray diffraction, X-ray reflectivity, grazing-incidence small-angle X-ray scattering and X-ray residual stress analysis. All the theoretical methods presented use the unified physical approach. This makes the book especially useful for readers learning and performing data analysis with different techniques. The theory is applicable to studies of bulk materials of all kinds, including single crystals and polycrystals as well as to surface studies under grazing incidence. The book appeals to researchers and graduate students alike.

This book primarily focuses on the fundamentals of and new developments in electrochemiluminescence (ECL), presenting high-quality content and explicitly aiming to summarize and disseminate the current state-of-the-art. The topics covered include the fundamental theory, mechanism, types of reactions involved, and the instrumental techniques. The book also examines the applications of ECL in many of the emerging fields of science, such as bioanalytical, analytical, clinical, pharmaceutical, forensic, military, microchip, TAS, and LED. It will be invaluable to bioanalysts, drug analysts, pharmaceutical researchers and other professionals worldwide, as well as to other interested readers.

The subject of this book is to introduce a model-based quantitative performance indicator methodology applicable for performance, cost and reliability optimization of non-volatile memories. The complex example of flash memories is used to introduce and apply the methodology. It has been developed by the author based on an industrial 2-bit to 4-bit per cell flash development project. For the first time, design and cost aspects of 3D integration of flash memory are treated in this book.

Cell, array, performance and reliability effects of flash memories are introduced and analyzed. Key performance parameters are derived to handle the flash complexity. A performance and array memory model is developed and a set of performance indicators characterizing architecture, cost and durability is defined.

Flash memories are selected to apply the Performance Indicator Methodology to quantify design and technology innovation. A graphical representation based on trend lines is introduced to support a requirement based product development process.

The Performance Indicator methodology is applied to demonstrate the importance of hidden memory parameters for a successful product and system development roadmap.

"Flash Memories "offers an opportunity to enhance your understanding of product development key topics such as:

. Reliability optimization of flash memories is all about threshold voltage margin understanding and definition;
. Product performance parameter are analyzed in-depth in all aspects in relation to the threshold voltage operation window;
. Technical characteristics are translated into quantitative performance indicators;
. Performance indicators are applied to identify and quantify product and technology innovation within adjacent areas to fulfill the application requirements with an overall cost optimized solution; . Cost, density, performance and durability values are combined into a common factor - performance indicator - which fulfills the application requirements"

This volume is a joint effort of the Research Materials Information Center (RMIC) of the Solid State Division at Oak Ridge National Laboratory and the Libraries and Information Systems Center at Bell Telephone Laboratories (BTL) Murray Hill, N. J. The Research Materials Information Center has, since 1963, been answering inquiries on the avail ability, preparation, and properties of inorganic solid-state research materials. The preparation of bibliographies has been essential to this function, and the interest in ferroelectrics led to the compila tion of the journal and report literature on that subject. The 1962 book Ferroelectric Crystals, by Jona and Shirane, was taken as a cutoff point, and all papers through mid-1969 received by the Center have been included. The Libraries and Information Systems Center of BTL has, over a period of years, developed a proprie tary package of computer programs called BELDEX, which formats and generates indexes to biblio graphic material. This group therefore undertook to process RMIC's ferroelectric references by BELDEX so that both laboratories could have the benefit of an indexed basic bibliography in this important research area.

This book provides an excellent overview on the most recent results on the industrial applications of Mossbauer spectroscopy attained on the fields of nanotechnology, metallurgy, biotechnology and pharmaceutical industry, applied mineralogy, energy production industry (coal, oil, nuclear, solar, etc.), computer industry, space technology, electronic and magnetic devices technology, ion implantation technology, including topics like characterization of novel construction materials, electronic components and magnetic materials, composite materials, colloids, amorphous and nanophase materials, small particles, coatings, interfaces, thin films and multilayers, catalysis, corrosion, tribology, surface modification, hydrogen storage, ball milling, radiation effects, electrochemistry, batteries, etc. From the various reports a broad overview emerges illustrating that the method can successfully be applied in a wide variety of topics.
Previously published in the journal Hyperfine Interactions."

This lecture notesbook presents how enhanced structural information of biomolecular ionscan be obtainedfrom interaction with photons of specific frequency - laser light. The methods described in the book ""Laser photodissociation and spectroscopy of mass-separated biomolecular ions"" make use of the fact that the discrete energy and fast time scale of "photoexcitation "can provide more control in ion activation. This activation is the crucial process producing structure-informative product ions that cannot be generated with more conventional heating methods, such as collisional activation. The book describes how the powerful separation capabilities and sensitivity of mass spectrometry (MS) can be combined with the structural insights from spectroscopy by measuring vibrational and electronic spectra of trapped analytes. The implementation of laser-based "photodissociation "techniques in MS requires basic knowledge of tunable light sources and ion trapping devices.

This book introduces the reader to key concepts and approaches in molecular spectroscopy, and the light sources and ion traps employed in such experiments. The power of the methods is demonstrated by spectroscopic interrogation of a range of important biomolecular systems, including "peptides," "proteins," and "saccharides," with laser light in the ultraviolet-visible, and infrared range. The book ""Laser photodissociation and spectroscopy of mass-separated biomolecular ions"" isan indispensable resource for students and researchers engaged or interestedin this emerging field. It provides the solid background of key concepts and technologies for the measurements, discusses state-of-the-art experiments, and provides an outlook on future developments and applications."

This thesis provides unique information on the Kerr-lens mode-locking (KLM) technique applied to a thin-disk laser. It describes in detail cavity geometry, the qualitative approach to KLM, and self-starting behavior in the regime of both negative and positive dispersion. Comprehensive comparative analysis of KLM and semiconductor saturable absorber techniques is also carried out. Recent successful experiments on carrier-envelope phase stabilization, spectral broadening and compression of output of this oscillator underline the importance of this new, emerging technology.

Proceedings of the 4th Joint International Conference on Hyperfine Interactions and International Symposium on Nuclear Quadrupole Interactions, HFI/NQI 2012 held in Beijing, China, September 10-14, 2012. The hyperfine interaction between the atomic nucleus and the surrounding charge distribution and the magnetic fields at the site of the nucleus remains a topic of high scientific interest. To this we have to add the field of nuclear quantum optics where the hyperfine interaction takes place between the atomic nucleus and synchrotron radiation. The study of this hyperfine interaction allows to shift the existing borders of scientific insight both in the properties of the atomic nucleus as in the properties of the solids and liquids in which it is imbedded. The 47 scientific contributions in this book describe studies presented at the HFI/NQI2012 conference. These studies are devoted to topics such as nuclear moments, nuclear polarization, fundamental interactions, magnetism and magnetic materials, semiconductors, metals, insulators, practical applications, developments in methodology and new directions in the field of hyperfine interactions.

The aim of this book is a discussion, at the introductory level, of some applications of solid state physics. The book evolved from notes written for a course offered three times in the Department of Physics of the University of California at Berkeley. The objects of the course were (a) to broaden the knowledge of graduate students in physics, especially those in solid state physics; (b) to provide a useful course covering the physics of a variety of solid state devices for students in several areas of physics; (c) to indicate some areas of research in applied solid state physics. To achieve these ends, this book is designed to be a survey of the physics of a number of solid state devices. As the italics indicate, the key words in this description are physics and survey. Physics is a key word because the book stresses the basic qualitative physics of the applications, in enough depth to explain the essentials of how a device works but not deeply enough to allow the reader to design one. The question emphasized is how the solid state physics of the application results in the basic useful property of the device. An example is how the physics of the tunnel diode results in a negative dynamic resistance. Specific circuit applications of devices are mentioned, but not emphasized, since expositions are available in the elec trical engineering textbooks given as references.

The author integrates discussions of fractal geometry, surface modeling techniques, and applications to real world problems to provide a comprehensive, accessible overview of the field. His work will equip researchers with the basic tools for measurement and interpretation of data, stimulating more work on these problems and, perhaps, leading to an understanding of the reasons that Nature has adopted this geometry to shape much of our world.

The solid molecular hydrogens are the simplest and most fundamental molecular solids. Except at ultrahigh pressures on the order of a few mega bars, where a transition to a metallic, atomic phase is expected, these solids are true molecular crystals in which the molecules retain their identity with properties not too different from those of the free molecules. At energies below the electronic excitation energy, the thermal and spectroscopic pro perties of these solids are determined by the translational, rotational, and intramolecular vibrational motions of the interacting molecules. The theo retical analysis of the solid-state properties in terms of the free molecules and the intermolecular interactions forms the main topic of this book. The available detailed knowledge of the properties of the free molecules makes it feasible to carry out this program to a large extent on the basis of first principles, and this is one of the attractive features of these systems. The solid hydrogens are dominated by quantum effects, the most out standing property being that the rotation of the molecules is free down to the lowest temperatures, in the sense that the rotational quantum number J characterizing the rotational motion of the free molecules remains a good quantum number in all of the solid-state phases except at ultrahigh pressures."

The Conference on the Science and Technology of Thin Film Superconductors was conceived in the early part of 1988 as a forum for the specialist in thin film superconductivity. The conference was held on November 14-18, 1988, in Co lorado Springs, Co lorado. Al though many excellent superconductivity conferences had been convened in the wake of the 1986-1987 discoveries in high temperature superconductivity, thin film topics were often dispersed among the sessions of a more general conference agenda. The response to the Conference on the Science and Technology of Thin Film Superconductors confirmed the need for an extended conference devoted to thin film superconductors. These proceedings are a major contribution to the technnology of thin film superconductivity because of the breadth and quality of the articles provided by leaders in the field. The proceedings are divided into articles on laser deposition, sputtering, evaporation, metal organic chemical vapor deposition, thick film, substrate studies, characterization, patterning and applications, and general properties. Most of the articles discuss scientific issues for high temperature thin film superconductors, although the conference was to be a forum for technology and scientific questions for both low and high temperature superconductivity. For the first day of the 5 day conference, Lawrence Berkeley Laboratory had organized an excellent set of short courses in superconduc t ing thin film devices.

The 6th International Conference on Laser Probing (LAP2012) had been held in Paris at the Institut Henri Poincare. It highlighted the state of the art in Laser Probing and reinforced the common ground and synergies among the different actors in the field. The Institut de Physique Nucleaire d Orsay and the Grand Accelerateur National d Ions Lourds in Caen had been in charge of the organization of this event, co-sponsored by the Institut National de Physique Nucleaire et de Physique des Particules (IN2P3) and the Laboratory Physique des 2 Infinis et des Origines (P2IO).
Previously published as special issue of Hyperfine Interactions, vol. 216, 1-3."

This report presents an account of the course "Nonlinear Spectroscopy of Solids: Advances and Applications" held in Erice, Italy, from June 16 to 30, 1993. This meeting was organized by the International School of Atomic and Molecular Spectroscopy of the "Ettore Majorana" Centre for Scientific Culture. The purpose of this course was to present and discuss physical models, mathematical formalisms, experimental techniques, and applications relevant to the subject of nonlinear spectroscopy of solid state materials. The universal availability and application of lasers in spectroscopy has led to the widespread observation of nonlinear effects in the spectroscopy of materials. Nonlinear spectroscopy encompasses many physical phenomena which have their origin in the monochromaticity, spectral brightness, coherence, power density and tunability of laser sources. Conventional spectroscopy assumes a linear dependence between the applied electromagnetic field and the induced polarization of atoms and molecules. The validity of this assumption rests on the fact that even the most powerful conventional sources of light produce a light intensity which is not strong enough to equalize the rate of stimulated emission and that of the experimentally observed decay. A different situation may arise when laser light sources are used, particularly pulsed lasers. The use of such light sources can make the probability of induced emission comparable to, or even greater than, the probability of the observed decay; in such cases the nonlinearity of the response of the system is revealed by the experimental data and new properties, not detectable by conventional spectroscopy, will emerge.

The interest in the problem of surface diffusion has been steadily growing over the last fifteen years. This is clearly evident from the increase in the number of papers dealing with the problem, the development of new experimental techniques, and the specialized sessions focusing on diffusion in national and international meetings. Part of the driving force behind this increasing activity is our recently acquired ability to observe and possibly control atomic scale phenomena. It is now possible to look selectively at individual atomistic processes and to determine their relative importance during growth and reactions at surfaces. The number of researchers interested in this problem also has been growing steadily which generates the need for a good reference source to farniliarize newcomers to the problem. While the recent emphasis is on the role of diffusion during growth, there is also continuing progress on the more traditional aspects of the problem describing mass transport in an ensemble of particles. Such a description is based on the statistical mechanical analysis of a collection of particles that mutually interact and develop correlations. An average over the multitude of atomistic processes that operate under these conditions is necessary to fully describe the dynamics in the system.

The aim of the workshop was to bring together specialists in various fields where non-exponential relaxation is observed in order to compare models and experimental results and to examine the general physical principles governing this type of behaviour. Non-exponential relaxation is found in extremely diverse physical systems all of which can be classified as complex. The form of the relaxation is generally parametrized using logarithmic, algebraic or stretched exponential decay forms. The conceptually simplest mechanism for the non-exponential decay is a spectrum of relaxation rates due to non-interacting units each of which relaxes with a different intrinsic time constant. Clear experimental examples can be given where for instance the relaxation of a collection of isolated polymer molecules leads to an overall stretched exponential decay. Non-exponential relaxation is observed in all strongly interacting complex systems (structural glasses, spin glasses, etc ... ) where each elementary unit is in interaction with many other units.

During August 24-27, 1993, approximately 60 scientists from the Americas, Europe and Japan, gathered in the city of Guanajuato, in the state of Guanajuato, Mexico, at the II Latin American Workshop on Magnetism, Magnetic Materials and their Applications. The group of scientists converging into the beautiful city of Guanajuato had come from Argentina, Chile, Brazil, Venezuela, Cuba, several places in Mexico, U. S. A. , Japan, Spain, France, Italy, Germany, Austria, Switzerland, and Denmark. The event attested to the success of the previous Workshop on Magnetism, Magnetic Materials and their Applications, held in Havana, Cuba, in 1991, as well as to the interest, level of activity and quality of the work being carried out in Latin America in the area of magnetism and magnetic materials. Equally important to everyone present was the fact that we had come to honor a friend, Professor L. M. Falicov, on his sixtieth birthday. The choice of a Latin American Workshop on magnetism as a Festschrift for Leo Falicov was, in our opinion, quite appropriate not only because of Leo's strong ties to Latin America, but also because of his superb contributions to science, and in particular, to magnetism. Professor Falicov was born in Buenos Aires, Argentina, where he spent a good part of his formative years.