Metallic Glass-Based Nanocomposites: Molecular Dynamics Study of Properties provides readers with an overview of the most commonly used tools for MD simulation of metallic glass composites and provides all the basic steps necessary for simulating any material on Materials Studio. After reading this book, readers will be able to model their own problems on this tool for predicting the properties of metallic glass composites. This book provides an introduction to metallic glasses with definitions and classifications, provides detailed explanations of various types of composites, reinforcements and matrices, and explores the basic mechanisms of reinforcement-MG interaction during mechanical loading. It explains various models for calculating the thermal conductivity of metallic glass composites and provides examples of molecular dynamics simulations. Aimed at students and researchers, this book caters to the needs of those working in the field of molecular dynamics (MD) simulation of metallic glass composites.

Flame Retardant Polymeric Materials provides a comprehensive and up-to-date overview of the field, from basic properties and mechanisms of action for flame retardants to emerging methods, materials, and industrial applications. With over 120 black and white images, Hu and Wang cover the latest in the development of novel polymer nanocomposites such as graphene, CNTs, LDHs, POSS, and techniques such as layer-by-layer assembly. These expert authors also include discussions on the important flame-retardant systems based on phosphorus, silicon, and boron. In doing so, they highlight the use of flame-retardants in varying industries, for example, construction, textiles, and aviation. This comprehensive handbook is an essential read for students and academics of physics with a particular interest in flame-retardant materials. It would also be recommended for professionals within the materials science and engineering fields.

The field of molecular medicine covers the medical interventions targeting molecular structures and mechanisms that are involved in disease progression. In cancer, several molecular mechanisms have been shown to impact its progression, aggressiveness and chemoresistance. Increasing evidence demonstrates the role of nanotechnology and outcome of molecular therapy. Several books have discussed molecular biology and mechanisms involved in cancer, but this text gives an account of molecular therapeutics in cancer relating to advancements of nanotechnology. It provides a description of the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology. Key Features: Provides current information in the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology Presents important aspects of nanotechnology in the site-specific delivery of anticancer agents Includes up to date information on oligonucleotide and gene based therapies in cancer Describes small targeted molecules, antibodies and oligonucleotides which have shown to selectively target the molecular structures thereby influencing signal transduction Facilitates discussion between researchers involved in cancer therapy and nanoscientists

Polymeric foams are sturdy yet lightweight materials with applications across a variety of industries, from packaging to aerospace. As demand for these materials increase, so does innovation in the development of new processes and products. This book captures the most dynamic advances in processes, technologies, and products related to the polymeric foam market. It describes the latest business trends including new microcellular commercialization, sustainable foam products, and nanofoams. It also discusses novel processes, new and environmentally friendly blowing agents, and the development and usage of various types of foams, including bead and polycarbonate, polypropylene, polyetherimide microcellular, and nanocellular. The book also covers flame-retardant foams, rigid foam composites, and foam sandwich composites and details applications in structural engineering, electronics, and insulation. Authored by leading experts in the field, this book minimizes the gap between research and application in this important and growing area.

Regulatory affairs and pharmacological drug safety issues of Ayurvedic medicine has been overlooked by practitioners for many years. Research in Ayurveda is now a world-wide phenomenon, and several large pharmaceutical corporations are investing money for novel drug discovery from Ayurvedic sources. This book examines the regulatory and pharmacological aspects and includes extensive data on scientific evaluation carried out on Ayurvedic formulations. It will also serve as a reference book on standardization, pre-clinical studies, and clinical and toxicological studies on Ayurvedic formulations.

Safely Design, Test, and Construct Products Made of Natural Fiber Composites Natural fibers and their composites carry distinct advantages over industrial fibers. Some advantages-including renewability and availability of raw materials, and lower energy consumption-could help safeguard environmental resources and eventually replace synthetic composites and conventional materials. Natural Fiber Composites explores the growing use of natural fibers in composites and covers material properties, treatment and processing, modeling, applications, design, and other vital information on this subject. Improve the Strength of Manufactured Composites, and Determine the Best Processing Technique Incorporating independent pieces written by a team of international contributors, this book enables readers to analyze and design structural components using state-of-the-art information and methods. It provides an overview of natural fiber composites, details the superior specific mechanical properties of these materials, and presents development techniques and design case studies that can improve performance and enhance the process. Natural Fiber Composites evaluates the value of natural fibers in composite materials, and offers introductory knowledge on natural fiber composites backed by internationally recognized experts in the field.

Heterophase polymerization is a century-old technology with a wide range of relevant industrial applications, including coatings, adhesives, rubbers, and many other specialized biomedical and high-performance materials. However, due to its multiscale complexity, it still remains a challenging research topic. It is a broad field covering all heterogeneous polymerization processes that result in polymer dispersions. Its technical realizations comprise emulsion polymerization, dispersion polymerization, suspension polymerization, miniemulsion polymerization, microemulsion polymerization, and others. This book is devoted to the science and technology of heterophase polymerization, considering it a generic term as well as an umbrella expression for all of its technical realizations. It presents, from a modern perspective, the basic concepts and principles required to understand the kinetics and thermodynamics of heterophase polymerization at the atomistic, molecular, macromolecular, supramolecular, colloidal, microscopic, mesoscopic, and macroscopic scales. It critically discusses the important physicochemical mechanisms involved in heterophase polymerization, such as nucleation, particle aggregation, mass transfer, swelling, spontaneous emulsification, and polymerization kinetics, along with the experimental evidences at hand.

A decade after publication of the first edition, Handbook of Venoms and Toxins of Reptiles responds to extensive changes in the field of toxinology to endure as the most comprehensive review of reptile venoms on the market. The six sections of this new edition, which has nearly doubled in size, complement the original handbook by presenting current information from many of the leading researchers and physicians in toxinology, with topics ranging from functional morphology, evolution and ecology to crystallography, -omics technologies, drug discovery and more. With the recent recognition by the World Health Organization of snakebite as a neglected tropical disease, the section on snakebite has been expanded and includes several chapters dealing with the problem broadly and with new technologies and the promises these new approaches may hold to counter the deleterious effects of envenomation. This greatly expanded handbook offers a unique resource for biologists, biochemists, toxicologists, physicians, clinicians, and epidemiologists, as well as informed laypersons interested in the biology of venomous reptiles, the biochemistry and molecular biology of venoms, and the effects and treatment of human envenomation.

Generally speaking, quantitative-structure activity relationship (QSAR) is a technique which correlates the biological activities of a set of compounds to their structures using a mathematical equation represented in its general form by Biological Activity = f (x1, ..., xn), where f is a mathematical function and x1, ..., xn are n molecular descriptors. Since the introduction of the initial concept of QSAR in the early 1960s, numerous advances have been introduced into the field transforming it into an essential tool in drug discovery and medicinal chemistry. Quantitative Structure - Activity Relationship: A Practical Approach provides a detailed overview of computational approaches in QSAR studies. It covers the applications of different algorithms in various steps of a QSAR analysis and shows clear examples. Each chapter introduces the tools and software involved. Moreover, challenges and issues which may be faced in any step of the analysis are thoroughly broken down based on the OECD guidelines, enabling the reader to familiarize themselves with potential end results. The book was kept concise, making it suitable for students (pharmacy, chemistry and biological science) and lecturers, as well as researchers in the field.

Since the 1990s the synthetic community has shown a growing interest in the development of catalytic reactions that employ entirely organic catalysts - so-called 'organocatalysts'. With the current emphasis on green chemistry throughout the chemical industry, organocatalysis has become indispensible. In spite of this growth and recognition, there can be a misconception that organocatalysts are only based on nitrogen-containing functional groups (amines, ureas, and quaternary ammonium salts, for example), and are only useful for asymmetric reactions. Nonnitrogenous Organocatalysis shows that the umbrella of organocatalysis covers other main group elements besides nitrogen, and the coverage is not just limited to asymmetric methods. Many of the catalysts and mechanisms discussed may not have a viable asymmetric variant or cannot be rendered asymmetric at all. This does not make them any less useful, as illustrated in this book.

The drug discovery and development process is getting longer, more expensive, and no better. The industry suffers from the same clinical attrition and safety-related market withdrawal rates today as it did 20 years ago. Industrialization of Drug Discovery: From Target Selection Through Lead Optimization scrutinizes these problems in detail, contrasting the promise of technology and industrialization with the challenges of using the tools available to their best advantage. The book explores early successes, examines the current state of the art, and provides a strategic analysis of the issues currently facing drug discovery. Introducing the historical background and current status of the industry, the book delineates the basic tenets underlying modern drug discovery, how they have evolved, and their use in various approaches and strategies. It examines, in detail, the regulations, requirements, guidelines, and draft documents that guide so many FDA actions. The editor devotes the remainder of the discussion to industrialization, compound and knowledge management functions, the drug screening process, collaboration, and finally, ethical issues. Drawing on real-life, from-the-trenches examples, the book elucidates a new approach to drug discovery and development. This modern-day, back-to-basics approach includes three steps: understand the science, unravel the story, and then intelligently apply the technology, bringing to bear the entire armamentarium of industrialization techniques, not just automation, to the discovery process. Using these steps, you can meet the goals of more specific targets, more selective compounds, and decreased cycle times. In effect, you can look for a bigger needle in a smaller haystack. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.

Lactic acid bacteria (LAB) are a diverse group of bacteria that comprise low GC content Gram-positive cocci or rods that produces lactic acid as the major end product of the fermentation process. Bifidobacterium genera may also be considered as a part of the LAB group for possessing some similar phenotypical characteristics despite the higher GC content. The key feature of LAB metabolism is efficient carbohydrate fermentation. This contributes to the production of several microbial metabolites that result in the improvement of flavor and texture of fermented foods, in addition to its positive impact on the human health when LAB is administered as a probiotic. The book deals with advances made in the functionalities of LAB, such as their effect on vitamin D receptor expression, impact on neurodegenerative pathologies, production of B-vitamins for food bio-enrichment, production of bacteriocins to improve gut microbiota dysbiosis, production of metabolites from polyphenols and their effects on human health, effect on reducing the immunoreaction of food allergens, as biological system using time-temperature to improve food safety, and the use of probiotics in animal feed. The book also reviews the use of LAB and probiotic technologies to develop new functional foods and functional pharmaceuticals.

Sub- and Supercritical Hydrothermal Technology: Industrial Applications offers a practical view of a variety of industrial applications and their challenges, offering a deep understanding of the application of sub- and supercritical fluids and their techno-economic viability. This book covers a wide range of applications of hydrothermal processing that result in almost zero waste, high energy efficiency, sustainable chemical processes, and minimal impact over the life cycle. These applications include processing of hazardous waste, bioproducts, coal, lipids, heavy oil and bitumen, and carbon materials. The use of hot-compressed water instead of different organic solvents, such as methanol, acetone, and hexane, is an environmentally benign, green, and sustainable option which can help to design chemical processes that support green chemistry and engineering. This book is pertinent for researchers and professionals in the fields of chemical engineering, industrial chemistry, environmental engineering, materials engineering, and manufacturing.

This new volume, the 7th in the Innovations in Agricultural & Biological Engineering book series, focuses on emerging trends, applications and challenges in food science and technology. While food science and technology is not a new field, it is constantly changing due to new technology, new science, and new demands. This multidisciplinary book not only considers food processing, preservation, and distribution, but it also taken into account the consumer's wants and needs. Included is a report of the status of agricultural production and food processing industries in India with a national and international perspective. The book then goes on to explore new and emerging trends in the science and technology in the field, including * applications of nuclear magnetic resonance in food processing and packaging management * ultrasound processing * application of biocomposite polymers in food packaging * bioprocessing and biorefinery approaches for sustainable fisheries * adding value to food from food waste through biotechnological intervention * functional foods and the fortification of foods Covering a broad selection of topics in the field, the volume will be of interest to food scientists and technologists, food process engineers, researchers, faculty and students, and many others the food science and technology industry.

There has been a growing interest in the health benefits derived from fruits and vegetables and the food products based on them. Many foods contain various phytochemicals, flavonoids, fibers, macronutrients and micronutrients, minerals, etc. that are good for health and essential for keeping good health. This volume provides a global perspective of the current state of food and health research, innovation, and emerging trends. It focuses on topics of food for better health, including functional foods and nutraceutical foods. The book is divided into several sections, covering: * Foods for Human Health Promotion and Prevention of Diseases, which include fruits, vegetables, and grains: their peels and fiber for better human health, health prospects of bioactive peptides derived from seed storage proteins, mushrooms as a novel source of antihyperlipidemic agents, and emerging foodborne illnesses and their prevention. * Specific Fruits, Spices and Dairy-Based Functional Foods for Human Health, which looks at the functional medicinal values of fenugreek, fruits as functional foods, and functional fermented dairy products. * Issues, Challenges, and Specialty Topics in Food Science, which focuses mainly on the stability issues of whole wheat flour, physicochemical properties and quality of food lipids, methods for food analysis and quality control, and interventions of ohmic heating technology in foods. The volume will be of interest to health practitioners, food specialists, nutrition producers and suppliers, practicing food process engineers, food technologists, researchers, food industry professionals, and faculty and upper-level students in food science.

Biopolymers are attracting immense attention of late because of their diverse applications that can address growing environmental concerns and energy demands. The development of various biomaterials creates significant advancements in the medical field as well, and many biopolymers are used for the fabrication of biomaterials. Together, biopolymers and biomaterials create great potential for new materials, applications, and uses. This new volume, Biopolymers and Biomaterials, covers the science and application of biopolymers and biomaterials. It presents an array of different studies on biopolymers and biomaterials, along with their results, interpretation, and the conclusions arrived at through investigations. It includes biopolymer synthesis, their characterizations, and their potential applications. The book begins with an explanation of the different biopolymers used in the textile industry, their advantages and disadvantages, and their applications.

Microbial lipases are industrially important and have gained attention due to their stability, selectivity, and broad substrate specificity. Lipases are used as medicine, and they also aid in indigestion, heartburn, allergy to gluten in wheat products (celiac disease), Crohn's disease, and cystic fibrosis. This volume considers the industrial demand for new sources of lipases with different catalytic characteristics that stimulate the isolation, growth, and development of new microbial strains. The volume narrates the challenging metagenomic approach with the isolation of the lipase gene, its cloning into Escherichia coli, culture of the recombinant bacteria, and extraction and assessment of the lipase enzyme. Lipase-producing bacteria are available in different habitats, such as industrial wastes, vegetable oil processing factories, dairy plants, and soils contaminated with oil and oil seeds, among others. This volume is the effort of the authors to document the scientific findings carried out over the last eight years in the area of un-culturable soil microorganisms. The book presents the physic-chemical features of lipases and their specific applications in different commercial industries. The in-depth study looks at metagenomics for lipases from all angles and provides a truly informative resource. It describes the biochemical characterization of lipase enzymes with the high activity in the presence of 1% tributyrin. A wide review has been presented in the book on lipase enzymes purified from a large collection of microbes present in soil, seawater, waste-dumping sites, animal systems (including human beings), and the atmosphere. Stability of enzymes over changing environments of the industry is indeed a big issue, and the book deals at length with the changing temperatures and pH and metal ion concentrations.

This informative volume discusses recent advancements in the research and development in synthesis, characterization, processing, morphology, structure, and properties of advanced polymeric materials. With contributions from leading international researchers and professors in academic, government and industrial institutions, Advanced Polymeric Materials for Sustainability and Innovations has a special focus on eco-friendly polymers, polymer composites, nanocomposites, and blends and materials for traditional and renewable energy. In this book the relationship between processing-morphology-property applications of polymeric materials is well established. Recent advances in the synthesis of new functional monomers has shown strong potential in generating better property polymers from renewable resources. Fundamental advances in the field of nanocomposite blends and nanostructured polymeric materials in automotive, civil, biomedical and packaging/coating applications are the highlights of this book.

This volume, Engineering Technology and Industrial Chemistry with Applications, brings together innovative research, new concepts, and novel developments in the application of new tools for chemical and materials engineers. It provides a collection of innovative chapters on new scientific and industrial research from chemists and chemical engineers at several prestigious institutions. It looks at recent significant research and reports on new methodologies and important applications in the fields of chemical engineering as well as provides coverage of chemical databases, bringing together theory and practical applications. Highlighting theoretical foundations, real-world cases, and future directions, this authoritative reference source will be a valuable addition for researchers, practitioners, professionals, and students of chemistry material and chemical engineering.

Technical and technological development demands the creation of new materials that are stronger, more reliable, and more durable-materials with new properties. This book skillfully blends and integrates polymer science, plastic technology, and rubber technology to highlight new developments and trends in advanced polyblends. The fundamentals of polymerization, polymer characteristics, rheology and morphology, as well as composition, technology, testing and evaluation of various plastics, rubbers, fibers, adhesives, coatings, and composites are comprehensively presented in this informative volume. The book presents the developments of advanced polyblends and the respective tools to characterize and predict the material properties and behavior. It provides important original and theoretical experimental results that use non-routine methodologies often unfamiliar to many readers. Furthermore chapters on novel applications of more familiar experimental techniques and analyses of composite problems are included, which indicate the need for the new experimental approaches that are presented. This new book: * Provides an up-to-date and thorough exposition of the present state of the art of polyblends and composites * Familiarizes the reader with new aspects of the techniques used in the examination of polymers, emphasizing plastic technology and rubber technology * Describes the types of techniques now available to the polymer chemist and technician and discusses their capabilities, limitations, and applications * Provides a balance between materials science and the mechanics aspects, basic and applied research, and high-technology and high-volume (low-cost) composite development Entrepreneurs and professionals engaged in production of as well as research and development in polymers will find the information presented here valuable and informative.

The aim of this book is to provide both a rigorous view and a more practical, understandable view of industrial chemistry and biochemical physics. This book is geared toward readers with both direct and lateral interest in the discipline. This volume is structured into different parts devoted to industrial chemistry and biochemical physics and their applications. Every section of the book has been expanded, where relevant, to take account of significant new discoveries and realizations of the importance of key concepts. Furthermore, emphases are placed on the underlying fundamentals and on acquisition of a broad and comprehensive grasp of the field as a whole. With contributions from experts from both the industry and academia, this book presents the latest developments in the identified areas. This book incorporates appropriate case studies, explanatory notes, and schematics for more clarity and better understanding. This new book: * Highlights some important areas of current interest in biochemical physics and chemical processes * Focuses on topics with more advanced methods * Emphasizes precise mathematical development and actual experimental details * Analyzes theories to formulate and prove the physicochemical principles * Provides an up-to-date and thorough exposition of the present state of the art of complex materials Topics include: * Photoelectrochemical properties of films of extra-coordinated tetrapyrrole compounds and their relationship with the quantum chemical parameters of the molecules * Bio-structural energy criteria of functional states in normal and pathological conditions * The ozone resistance of covulcanizates butadiene-nitrile rubbers with chlorinated ethylene-propylene-diene elastomers * Ways of regulation of release of medicinal substances from chitosan films * Environmental durability of powder polyester paint coatings * Ozone decomposition * Design and synthesis of its derivative with enhanced potential to scavenge hypochlorite radical scavenging capacity of n-(2-mercapto-2-methylpropionyl)-L-cysteine * Bacterial poly(3-hydroxybutyrate) as a biodegradable polymer for biomedicine * Designing, analysis, and industrial use of the dynamic spray scrubber * Magnetic properties of organic paramagnet * The effect of antioxidant drug mexidol on bioenergetic processes and nitric oxide formation in the animal tissues

This book presents some fascinating phenomena associated with the remarkable features of high performance polymers and also provides an update on applications of modern polymers. It offers new research on structure-property relationships, synthesis, and purification, and potential applications of high performance polymers. The collection of topics in this book reflects the diversity of recent advances in modern polymers with a broad perspective that will be useful for scientists as well as for graduate students and engineers. The book helps to fill the gap between theory and practice. It explains the major concepts of new advances in high performance polymers and their applications in a friendly, easy-to-understand manner. The book opens with a presentation of classical models, moving on to increasingly more complex quantum mechanical and dynamical theories. Coverage and examples are drawn from modern polymers.

This volume presents the various categories of high performance materials and their composites and provides up-to-date synthesis details, properties, characterization, and applications for such systems to give readers and users better information to select the required material. The volume provides the following features: * Includes a wide range of high performance and engineering materials * Details the synthesis and properties of each of new materials * Presents practical industrial applications * Contains material written by some of the world's most well-known and respected experts in the field

This book provides a broad overview of current studies in the engineering of polymers and chemicals of various origins. The innovative chapters cover the growth of educational, scientific, and industrial research activities among chemists, biologists, and polymer and chemical engineers. This book publishes significant research and reviews reporting new methodologies and important applications in the fields of industrial chemistry, industrial polymers, and biotechnology, as well the latest coverage of chemical databases and the development of new computational methods and efficient algorithms for chemical software and polymer engineering.

This book provides a vast amount of information on new approaches, limitations, and control on current polymers and chemicals complexity of various origins, on scales ranging from single molecules and nano-phenomena to macroscopic chemicals. Starting with a detailed introduction, the book is comprised of chapters that survey the current progress in particular research fields. The chapters, prepared by leading international experts, yield together a fascinating picture of a rapidly developing research discipline that brings chemical technology and polymers to new frontiers.