This book examines the social inequalities relating to food insecurity in the UK, as well as drawing parallels with the US. Access to food in the UK, and especially access to healthy food, is a constant source of worry for many in this wealthy country. Crises, such as the COVID-19 pandemic, have coincided with a steep rise in the cost of living, meaning household food insecurity has become a reality for many more households. This book introduces a new framework to examine the many influences on local-level food inequalities, whether they result from individual circumstances or where a person lives. The framework will allow researchers new to the field to consider the many influences on food security, and to support emerging research around different sub-topics of food access and food security. Providing a thorough background to two key concepts, food deserts and food insecurity, the book documents the transition from area-based framing of food resources, to approaches which focus on household food poverty and the rise of food banks. The book invites researchers to acknowledge and explore the ever changing range of place-based factors that shape experiences of food insecurity: from transport and employment to rural isolation and local politics. By proposing a new framework for food insecurity research and by drawing on real-world examples, this book will support academic and applied researchers as they work to understand and mitigate the impacts of food insecurity in local communities. This book will be of great interest to students and scholars of food and nutrition security, public health, and sociology. It will also appeal to food policy professionals and policymakers who are working to address social inequalities and improve access to healthy and nutritious food for all.

What is the best way to cold settle my white juices? How do I sample for Brettanomyces? What s the best procedure to clean or store a used barrel? How do I care for the winery pump? My wine is too astringent - what do I do? When can I skip filtering my wine? When will it re-ferment and push the corks? How do I best store and ship my bottled wine?
Expert answers to these and further questions that arise during winemaking can be found in this convenient reference book. Arranged in practical question and answer format, Winemaking problems solved provides brief, quickly accessible solutions to more than one hundred issues of frequent concern to winemaking professionals.
Chapters review issues associated with grape analysis, juice and must preparation, yeast and malolactic fermentation, wine clarification and stabilisation, filtration, packaging and storage. Sections on winery equipment maintenance and troubleshooting, wine microbiology and sanitation are also included. The final part of the book focuses on particular wine quality issues, such as hazes and off-odours.
With expert contributions from a diverse team of international enologists, Winemaking problems solved is an essential, hands-on reference for professionals in the winemaking industry and students of enology.
Provides solutions to a variety of issues of frequent concern to wine making professionalsReviews issues related to grape analysis, filtration, packaging and microbiologyA hands-on reference book written by a diverse team of international enologists"

Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The information is presented in an up-to-date review form with an underlying and fundamental focus on the educational aspects. Beginning with an introduction to drug design and discovery, the first eight chapters cover molecular recognition, ligand-based drug design, and biostructure-based drug design. The authors also discuss drug-like properties and decision making in medicinal chemistry, chemical biology, natural products in drug discovery, and in vivo imaging in drug discovery. The middle six chapters provide an overview of peptide and protein drug design, prodrugs in drug design and development, and enzyme inhibitors. The authors also go through receptors (structure, function, and pharmacology), ion channels (structure and function), and neurotransmitter transporters (structure, function, and drug binding). The following chapters address important neurotransmitter systems, GABA and glutamic acid receptors and transporter ligands, acetylcholine, histamine, dopamine and serotonin, and opioid and cannabinoid receptors. The book concludes with an examination of neglected diseases, anticancer agents, tyrosine kinase receptors, and antibiotics.

"Biodegradable Composites for Packaging Applications" describes design, processing, and manufacturing of advanced biodegradable composites in packaging industry applications. It covers fundamentals of biodegradable polymers followed by introduction to biodegradable materials for food packaging industry and its processing mechanisms. Pertinent applications are explained across different chapters including intelligent packaging, applied technologies, degradation problems and its impact on environment and associated challenges. Features Covers biodegradable composites and targeted applications in packaging for industrial applications. Includes exhaustive processing and characterizations of biodegradable composites. Discusses innovative commodities packaging applications. Reviews advanced integrated design and fabrication problems for conductive and sensors applications. Explores various properties and functionalities through extensive theoretical and experimental modeling. This volume is aimed at researchers and graduate students in sustainable materials, composite technology, biodegradable plastics, and food technology and engineering.

Provides insight to extremophiles. Unveils the mysticism of extreme environments. Explores applications of extremophiles in biorefineries. Throws light on the advancement of industrially important extremozymes. Explores applications in biofilms and microbial corrosion.

2020 JAMES BEARD AWARD WINNER JANCIS ROBINSON - 2020 JAMES BEARD COOKBOOK HALL OF FAME HONOREE "The most useful single volume on wine ever published... If I owned only one wine book, it would be this one." - Andrew Jefford, Decanter A major new edition of this landmark wine book that has sold 4.7 million copies worldwide. Few wine books can be called classic, but the first edition of The World Atlas of Wine made publishing history when it appeared in 1971. It is recognized by critics as the essential and most authoritative wine reference work available. This eighth edition will bring readers, both old and new, up to date with the world of wine. To reflect all the changes in the global wine scene over the past six years, the Atlas has grown in size to 416 pages and 22 new maps have been added to the wealth of superb cartography in the book. The text has been given a complete overhaul to address the topics of most vital interest to today's wine-growers and drinkers. With beautiful photography throughout, Hugh Johnson and Jancis Robinson, the world's most respected wine-writing duo, have once again joined forces to create a classic that no wine lover can afford to be without. "The World Atlas of Wine is the single most important reference book on the shelf of any wine student." - Eric Asimov, New York Times "Like a good bottle of wine, you'll find yourself going back to it again and again... Perfect for anyone who has a thirst for greater wine knowledge." - Edward Deitch, NBC/today.com "The World Atlas of Wine belongs on your shelf... The essential rootstock of any true wine lover's library. A multi-layered snapshot of wine and how it has evolved." - Dave McIntyre, Washington Post A "masterwork" and a "must-have" - Food & Wine Winner Andre Simon Award Best Drinks Book of 2019 Shortlisted for the Louis Roederer Wine Book of the Year 2020

Phytochemicals and Medicinal Plants in Food Design: Strategies and Technologies for Improved Healthcare explores the therapeutic potential of various natural and novel phytochemicals in the design of new foods. Divided into two parts, the first section discusses plant-based secondary metabolites for healthcare, focusing on the health aspects of herbs and medicinal plants and nutraceuticals for livestock production and for the treatment of diseases such as HIV and diabetes. The authors also address the benefits of preserving indigenous knowledge of medicinal plants and current consumer views of health issues from foods. The second part delves into the design and utilization of healthy foods. This section discusses the application of novel designs and herbal formulations in conjunction with other biomolecules for the development and utilization for food products with health benefits. Key features: Encourages the preservation of indigenous knowledge on herbs and medicinal plants Explains the health-promoting effects of some herbs and medicinal plants Discusses the therapeutics and their mechanisms of actions of the biological compounds for food safety This informative volume will be valuable for faculty, students, scientists, researchers, and industry professionals in the development of superfoods from phytochemicals and medicinal plants.

The Art and Science of Dermal Formulation Development is a comprehensive guide to the theory and practice of transdermal and topical formulation development, covering preclinical studies, evaluation, and regulatory approval. It enables the reader to understand the opportunities and challenges in developing products and how risks can be mitigated. Over the last 25 years, expertise in this area has declined whilst drug delivery systems for other administration routes have developed significantly. The advantages offered by transdermal and topical drug delivery remain compelling for sectors including the pharmaceutical industry, personal care, and cosmetics. This text addresses the dearth of expertise and discusses how skin can be a route of delivery and the processes in formulation development, but how such an application is very different to that used for oral, IV, and other administration routes. Key Features: Presents a practical guide for both industry and academia Focuses on and draws together the fundamental principles behind transdermal and topical drug delivery Illustrates the practicalities of formulation design using key case studies Gives an understanding of the skin as a route of delivery and how formulation development for such application differs from that for other administration routes

Covers broad areas such as chemical properties, bioactive components and health benefits of tea-based foods Focuses on chemical properties of tea foods, processing technologies, functional food products, and health benefits Explains how the addition of tea extract changes the properties of food and consumers sensory perception

This book offers a broad summary of the wild plants and their usage, as well as the growing interest in ethnopharmacology research. The book comprises of important issues such as diversity of wild plants with emphasis on medicinal and food plants, threats to wild plants and traditional ethnobotanical knowledge, their uses in skin diseases, snake-bites, in cosmeceuticals, etc. Moreover, the ethnopharmacological relevance of wild plants in Latin America has been discussed. The chapters include a wide range of case studies, giving updated evidence on the importance of their wild plant resources from different countries including Peru, Nepal, Bangladesh, India, Pakistan, Brazil. In addition, some specific species are used to explain their potential properties, as well as the dangers of their use without guidance of trained natural healers. The book discusses traditional usage and properties of wild plants and is entirely different from other related publications and useful for the researchers working in the areas of conservation biology, botany, ethnobiology, ethnopharmacology, policymakers, etc.

Plant-Based Functional Foods and Phytochemicals: From Traditional Knowledge to Present Innovation covers the importance of the therapeutic health benefits of phytochemicals derived from plants. It discusses the isolation of potential bioactive molecules from plant sources along with their value to human health. It focuses on physical characteristics, uniqueness, uses, distribution, traditional and nutritional importance, bioactivities, and future trends of different plant-based foods and food products. Functional foods, beyond providing basic nutrition, may offer a potentially positive effect on health and cures for various disease conditions, such as metabolic disorders (including diabetes), cancer, and chronic inflammatory reactions. The volume looks at these natural products and their bioactive compounds that are increasingly utilized in preventive and therapeutic medications and in the production of pharmaceutical supplements and as food additives to increase functionality. It also describes the concept of extraction of bioactive molecules from plant sources, both conventional and modern extraction techniques, available sources, biochemistry, structural composition, and potential biological activities.

Provides insight about application of natural fibers in polymer and composite manufacturing Covers fundamental concepts for the characterization of natural fiber composites Describes extraction process of natural fibers with comparison Includes comparative study of different polymer matrices Discusses diverse applications and scope for commercialization and entrepreneurship

With easily accessible oil reserves dwindling, petroleum engineers must have a sound understanding of how to access technically challenging resources, especially in the deepwater environment. These technically challenging resources bring with them complexities around fluid flow not normally associated with conventional production systems, and engineers must be knowledgeable about navigating these complexities. Practical Aspects of Flow Assurance in the Petroleum Industry aims to provide practical guidance on all aspects of flow assurance to offer readers a ready reference on how to ensure uninterrupted transport of processed fluids throughout the flow infrastructure by covering all practical aspects of flow assurance, being written in such a way that any engineer dealing with the oil and gas industry will be able to understand the material, containing solved examples on most topics, placing equal emphasis on experimental techniques and modeling methods, and devoting an entire chapter to the analysis and interpretation of published case studies. With its balance of theory and practical applications, this work provides petroleum engineers from a variety of backgrounds with the information needed to maintain and enhance productivity.

The field of nanocatalysis is undergoing rapid development. Nanocatalysis can help in designing catalysts with excellent activity, greater selectivity, and high stability. Their properties can easily be tuned by tailoring the size, shape, and morphology of the particular nanomaterial. Exhibiting both homogeneous and heterogeneous catalytic properties, nanocatalysts allow for rapid and selective chemical transformations, with the benefits of excellent product yield and ease of catalyst separation and recovery. Nanocatalysis: Synthesis of Bioactive Heterocycles reviews the catalytic performance and the synthesis and characterization of nanocatalysts, examining the current state of the art and pointing the way towards new avenues of research specially synthesis of bioactive heterocycles. Top researchers summarize synthetic methodologies for the synthesis of bioactive heterocycles using a nanocatalytic framework. The catalytic performance and the synthesis and characterization of nanocatalysts are reviewed. State of the art methods and new and emerging applications of nanocatalysts in the synthesis of biologically active heterocycles are detailed. Additional features include: Focuses on designing and synthesizing nanocatalysts specifically for the synthesis of different bioactive heterocycles. Demonstrates how nanocatalysis can produce catalysts with excellent activity, greater selectivity, and high stability. Explores tuning catalysts properties by tailoring the size, shape, and morphology of a nanomaterial. Offers the reader insights into the field of nanoscience via nanocatalysis. Nanocatalysis: Synthesis of Bioactive Heterocycles is a must read for researchers in organic chemistry, medicinal chemistry and biochemistry.

New perspectives on how to successfully drive changes in companies' process safety management systems Simply learning from process safety incidents has proven to be insufficient to drive performance improvements. To truly change, organizations must seek out & embed learnings in their programs & systems. This book picks up from previous CCPS books, Incidents That Define Process Safety and Investigating Process Safety Incidents. This important book: Offers guidelines for improving process safety performance by embedding the lessons learned from publicly available investigations Recommends a continuous improvement learning model focused on organizational learning Provides examples for using the model's techniques to drive -continuous improvements Contains an index of more than 400 investigated incidents and introduces the concept of Drilldown to help find lessons that might not have been mentioned before. Written for safety professionals and process safety consultants, Driving Continuous Process Safety Improvement from Investigated Incidents is a hands-on guide for adopting a model for successfully driving the learnings from process safety incident investigations.

Real-world evidence (RWE) has been at the forefront of pharmaceutical innovations. It plays an important role in transforming drug development from a process aimed at meeting regulatory expectations to an operating model that leverages data from disparate sources to aid business, regulatory, and healthcare decision making. Despite its many benefits, there is no single book systematically covering the latest development in the field. Written specifically for pharmaceutical practitioners, Real-World Evidence in Drug Development and Evaluation, presents a wide range of RWE applications throughout the lifecycle of drug product development. With contributions from experienced researchers in the pharmaceutical industry, the book discusses at length RWE opportunities, challenges, and solutions. Features Provides the first book and a single source of information on RWE in drug development Covers a broad array of topics on outcomes- and value-based RWE assessments Demonstrates proper Bayesian application and causal inference for real-world data (RWD) Presents real-world use cases to illustrate the use of advanced analytics and statistical methods to generate insights Offers a balanced discussion of practical RWE issues at hand and technical solutions suitable for practitioners with limited data science expertise

The first edition of Food processing technology was quickly adopted as the standard text by many food science and technology courses. This completely revised and updated third edition consolidates the position of this textbook as the best single-volume introduction to food manufacturing technologies available. This edition has been updated and extended to include the many developments that have taken place since the second edition was published. In particular, advances in microprocessor control of equipment, minimal processing technologies, functional foods, developments in active or intelligent packaging, and storage and distribution logistics are described. Technologies that relate to cost savings, environmental improvement or enhanced product quality are highlighted. Additionally, sections in each chapter on the impact of processing on food-borne micro-organisms are included for the first time.
Introduces a range of processing techniques that are used in food manufacturingExplains the key principles of each process, including the equipment used and the effects of processing on micro-organisms that contaminate foodsDescribes post-processing operations, including packaging and distribution logistics"

This book provides a review of innovative and novel biotechnological techniques that can be implemented to assess, analyze, and mitigate harmful pollutants and wastes that result from agricultural and industrial operations. It helps to meet the much-needed demand for improvement of low-cost technologies that tackle pollution problems scientifically for the safeguard of the environment, focusing on bioremediation solutions that also create useful and renewable forms of energy. The biotechnological interventions discussed in the volume include approaches involving genomics, proteomics, transcriptomics, metabolomics, and fluxomics. In addition, biological agents such as microalgae, bacteria, fungi, and bacteriophage, which can also prove to be helpful in the elimination of wastes, are explored. Topics in Environmental Biotechnology: Sustainable Remediation of Contamination in Different Environs include the associated consequences and hazards from agricultural and industrial waste and a variety of bioremediation measures, including the use of bioaugmentation, biosensors, challenges of biofuel production, and more. The book is directed to researchers, scientists, industrialists, farmers, agricultural waste management authorities, as well as to faculty and students, and aims to help implement these novel technologies for environmental stability.

Food Processing and Preservation Technology: Advances, Methods, and Applications confronts the challenges of food preservation by providing new research and information on the use of novel processing and preservation technologies during production, processing, and transportation in the food industry for the improvement of shelf life and the safety of foods. The book is organized in two main parts. The first section focuses on novel and nonthermal processing of food and food products. It looks at dielectric heating and ohmic heating as well as three-dimensional printing of foods and ozonization of food products. Part two delves into process interventions for food processing and preservations, discussing the applications of diverse novel food processing. The authors discuss drying technologies, advances in food fermentation technologies, mechanization of traditional indigenous products for preservation of food and safety, and different properties and concepts of bakery products. Key features: Examines different properties and attributes of some bakery foods, etc. Elucidates on novel nonthermal processing techniques and their mechanisms of actions for minimal loss of food nutrients and for food safety Discusses a variety of modern technologies that aim to reduce the spoilage of food products This volume presents valuable research on food processing, quality control, and safety measures for food products by means of novel processing and preservation technologies during production, processing, and transportation in the food industry.

This book is a comprehensive review of thrombin, especially as regulatory protease. The ready availability of highly purified thrombin has stimulated rapid advances in the cell biology of this important macromolecule. The text focuses on research findings from the discovery of thrombin by Andrew Buchanan in 1842 to the present. A substantial amount of this work was conducted by the author and his colleagues. His work on the purification of thrombin was seminal to much subsequent work on thrombin. This volume provides a framework for future studies now made possible by the discovery of the importance of exosites in the physiology of thrombin function. The current work describes the process of the development of an oral inhibitor of thrombin used in the prevention of thrombosis. Key Features Reviews the history of Thrombin (Fibrin Ferment) Documents the relation of protein engineering and chemical modification in the study of thrombin Summarizes the interaction of thrombin with fibrinogen and fibrin Outlines the role of exosites in thrombin function Describes the development of an oral inhibitor for thrombin

Consistent explanation of all basic principles of cavitation. Scientific background for engineering applications. Modern theory and experimental results. Contains objective discussions of controversial issues. Can be used by students.

Properties and Formulation: From Theory to Real-World Application Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone or completely derail important new drug development. Even the much-needed reformulation of currently marketed products can be significantly affected by these challenges. More recently it was reported that the percentage increased to 90% for the candidates of new chemical entities in the discovery stage and 75% for compounds under development. In the most comprehensive resource on the topic, this third edition of Water-Insoluble Drug Formulation brings together a distinguished team of experts to provide the scientific background and step-by-step guidance needed to deal with solubility issues in drug development. Twenty-three chapters systematically describe the detailed discussion on solubility theories, solubility prediction models, the aspects of preformulation, biopharmaceutics, pharmacokinetics, regulatory, and discovery support of water-insoluble drugs to various techniques used in developing delivery systems for water-insoluble drugs. This book includes more than 15 water-insoluble drug delivery systems or technologies, illustrated with case studies and featuring oral and parenteral applications. Highlighting the most current information and data available, this seminal volume reflects the significant progress that has been made in nearly all aspects of this field. The aim of this book is to provide a handy reference for pharmaceutical scientists in the handling of formulation issues related to water-insoluble drugs. In addition, this book may be useful to pharmacy and chemistry undergraduate students and pharmaceutical and biopharmaceutical graduate students to enhance their knowledge in the techniques of drug solubilization and dissolution enhancement.

Biologics and Biosimilars: Drug Discovery and Clinical Applications is a systematic integration and evaluation of all aspects of biologics and biosimilars, encompassing research and development, clinical use, global regulation, and more. Biosimilars are biological therapeutic agents designed to imitate a reference biologic with high similarities in structure, efficacy, and safety, but also with potential clinical effective and cost-efficient options for the manufacturers, payers, clinicians, and patients. Most of the top-selling prescription drugs in the current market are biologics, which have revolutionized the treatment strategies and modalities for life-threatening and/or rare diseases. This book outlines the key processes and challenges in drug development, regulations, and clinical applications of biologics, biosimilars, and even interchangeable biosimilars. Global experts in the field discuss essential categories and prototype drugs of biologics and biosimilars in clinical practice such as allergenics, blood and blood components, cell treatment, gene therapy, recombinant therapeutic proteins or peptides, tissues, and vaccines. Additional features: Integrates the latest bench and bedside evidence of drug development and regulations of biologics and biosimilars Contains key study questions for each chapter to guide the readers, as well as drug charts for all therapeutic applications of biologics and biosimilars Presents detailed schematic illustrations to explain the drug development, clinical trials, regulations, and clinical applications of biologics and biosimilars This book is an invaluable tool for health care professional students, providers, and pharmaceutical and health care industries, as well as the public, providing readers with educational updates about the drug development and clinical affairs of biological medications and their similar drugs.

Gives basics of Fortran and Numerical Calculation. The book includes Fortran codes and also gives access to author's website. Summarizes history of Quantum Mechanics through the most important papers. Presents detailed mathematical basis of Quantum Mechanics and Quantum Chemistry. Includes proposed exercises and do-it-yourself activities.

The Routledge International Handbook of Green Criminology was the first comprehensive and international anthology dedicated to green criminology. It presented green criminology to an international audience, described the state of the field, offered a description of a range of environmental issues of regional and global importance, and argued for continued criminological attention to environmental crimes and harms, setting an agenda for further study. In the six years since its publication, the field has continued to grow and thrive. This revised and expanded second edition of the Handbook reflects new methodological orientations, new locations of study such as Asia, Canada and South America, and new responses to environmental harms. While a number of the original chapters have been revised, the second edition offers a range of fresh chapters covering new and emerging areas of study, such as: conservation criminology, eco-feminism, environmental victimology, fracking, migration and eco-rights, and e-waste. This handbook continues to define and capture the field of green criminology and is essential reading for students and researchers engaged in green crime and environmental harm.