Rediscover the economic potential of growing Ribes cultivars in the United States and Canada! Currants, Gooseberries, and Jostaberries: A Guide for Growers, Marketers, and Researchers in North America explores the biology and history of growing these small fruits as commercial crops in North America. This book provides authoritative information on the potential risks and profits of establishing a currant or gooseberry farm and offers step-by-step details for cost-effective set-up, maintenance, and post-harvest activities. This book will be a reliable reference for prospective growers and Ribes researchers. Currants, Gooseberries, and Jostaberries presents in detail the necessary components of successful Ribes culture farming, including: site and soil selection design of planting site plant propagation cultivar selection cultural practice pest and disease management harvesting and marketing The book supplies the latest production figures for Ribes crops worldwide to help you choose which crops to grow. It also contains detailed information on fruit biochemistry, allowing you to market to human health industries. Currants, Gooseberries, and Jostaberries is the first North American publication to focus exclusively on Ribes culture in more than 50 years. It's your one-stop resource for up-to-date information this side of the Atlantic Ocean. Currants, Gooseberries, and Jostaberries provides you with tables, figures, and appendices, such as a table of the state regulations governing the importation and growing of currants, gooseberries, and jostaberries as listed by the Department of Agriculture calendars of what you need to do throughout the year to prepare, plant, and manage Ribes crops a list of cultivars available in North America tables of suggested parentage for currants and gooseberries to breed for improved fruit and juice quality, disease resistance or frost resistance, or improved mechanics for harvest a site selection checklist an enterprise budget showing typical costs of producing currants and gooseberries for sale in the market

The treatment of children with medicinal products is an important scientific area. It is recognized that many medicines that are used extensively in pediatric patients are either unlicensed or off-label. This textbook will help pediatric health professionals select the most appropriate medication to effectively treat children and ensure minimal side effects.

Pharmaceutical product development is a multidisciplinary activity involving extensive efforts in systematic product development and optimization in compliance with regulatory authorities to ensure the quality, efficacy and safety of resulting products. Pharmaceutical Product Development equips the pharmaceutical formulation scientist with extensive and up-to-date knowledge of drug product development and covers all steps from the beginning of product conception to the final packaged form that enters the market and lifecycle management thereof. Applications of core scientific principles for product development are also thoroughly discussed in conjunction with the latest approaches involving design of experiment and quality by design with comprehensive illustrations based on practical case studies of several dosage forms. The book presents pharmaceutical product development information in an easy-to-read mode with simplified theories, case studies and guidelines for students, academicians and professionals in the pharmaceutical industry. It is an invaluable resource and hands-on guide covering managerial, regulatory and practical aspects of pharmaceutical product lifecycle management.

In developing countries, access to affordable medicines for the treatment of diseases such as AIDS and malaria remains a matter of life or death. In Africa, for instance, more than one million children die each year from malaria alone, a figure which could soon be far higher with the extension of patent rules for pharmaceuticals. Previously, access to essential medicines was made possible by the supply of much cheaper generics, manufactured largely by India; from 2005, however, the availability of these drugs is threatened as new WTO rules take effect. Halting the spread of malaria and HIV/AIDS is one of the eight Millennium Goals adopted at the UN Millennium Summit, which makes this a timely and topical book. Informed analysis is provided by internationally renowned contributors who look at the post-2005 world and discuss how action may be taken to ensure that intellectual property regimes are interpreted and implemented in a manner supportive to the right to protect public health and, in particular, to promote access to medicines for all.

Advances in the flavonoid field have been nothing short of spectacular over the last 20 years. While the medical field has noticed flavonoids for their potential antioxidant, anticancer and cardioprotectant characteristics, growers and processors in plant sciences have utilized flavonoid biosynthesis and the genetic manipulation of the flavonoid pathway in plants to improve the nutritional and ornamental value of crops. Flavonoids: Chemistry, Biochemistry and Applications covers each class of flavonoid and presents the historic advances made in flavonoid research since the 1994 publication of an earlier text, Flavonoids Advances in Research Since 1986. This book details the analytical techniques scientists have used to achieve an improved understanding of flavonoid structures and functions as well as advances in the genetic manipulation of the flavonoid pathway, and the discovery of many new flavonoids. It indicates which techniques are best suited for the isolation and structure determination of flavonoids and whether the structures are novel. While explaining how to evaluate the flavonoid content in food and beverages, the book reveals the biotechnological advances that have allowed nutritionists and plant physiologists to assess the possible effects of flavonoids. As interest regarding the impact and health benefits of flavonoids continues to grow, Flavonoids: Chemistry, Biochemistry and Applications reflects the continuing commitment of flavonoid researchers to the improvement of human health and provides the most comprehensive, up-to-date source of information for all known flavonoids.

3D and 4D Printing of Polymer Nanocomposite Materials: Processing, Applications, and Challenges covers advanced 3D and 4D printing processes and the latest developments in novel polymer-based printing materials, thus enabling the reader to understand and benefit from the advantages of this groundbreaking technology. The book presents processes, materials selection, and printability issues, along with sections on the preparation of polymer composite materials for 3D and 4D printing. Across the book, advanced printing techniques are covered and discussed thoroughly, including fused deposition modeling (FDM), selective laser sintering (SLS), selective laser melting (SLM), electron beam melting (EBM), inkjet 3D printing (3DP), stereolithography (SLA), and 3D plotting. Finally, major applications areas are discussed, including electronic, aerospace, construction and biomedical applications, with detailed information on the design, fabrication and processing methods required in each case.

Finding current, detailed information on the analysis of drug-related compounds is challenging at best. While almost everyone engaged in the study of these compounds has accumulated a vast variety of data over time, a single-source, comprehensive review of that data would be an invaluable resource to have. Instrumental Data for Drug Analysis (IDDA), Third Edition is that resource, presenting the latest information on these compounds in a thorough, straightforward format. What's new in the Third Edition: Presents FT-Raman Spectra tables Includes information and analysis relating to 125 new drugs, including Zoloft, Claritin, Ambien, and the latest generation of narcotics Organizes information on each drug in a simple, streamlined format

The ultimate course for wine lovers! Learn your sauvignon blanc from your chardonnay and your merlot from your grenache. Smell, swirl and taste your way to transforming from wine novice to expert. The pages of this wine book make a comprehensive, no-nonsense wine tasting course that covers every aspect of wine from grape to glass. Explore the nuances of your favourite red and white and discover new cultivars. Inside, you'll find: - A dynamic course in understanding wine - through tasting and appreciation - with every subject given a high-impact visual treatment - A structure that reflects how people approach wine - talking, tasting, and buying wine come before exploring grape varieties and wine regions - All key wine subjects covered, shown, and explained in an easy-to-understand way - Themed tasting exercises are located throughout the book, encouraging readers to learn at their own pace Follow expert wine advice in the latest edition of Wine: A Tasting Course. The updated text and refreshed design bring concepts to life such as food and wine pairing, identifying the style spectrum, and distinguishing taste and smell. It explores fun wine facts and explodes myths, giving you everything you need to talk, taste, and enjoy your favourite vintage. Can't smell honeysuckle in that glass of sauvignon blanc, or wondering which end of a bottle of chianti is the "nose"? With this immersive guide to all things wine, you'll soon become an expert. Pour over vibrant infographics and learn through "Did you know?" boxes as you try out a selection of taste tests and get a handle on grape varieties and regions. This wine guide is a beautiful gift for the wine-lover in your life or the book for beginners you've been searching for to enjoy, understand, and appreciate wine.

Serving as an all-in-one guide to the entire field of coatings technology, this encyclopedic reference covers a diverse range of topics-including basic concepts, coating types, materials, processes, testing and applications-summarizing both the latest developments and standard coatings methods. Take advantage of the insights and experience of over 100 recognized experts in over 100 chapters to select and apply the best coatings for your own product needs. Emphasizing an interdisciplinary exchange of ideas and approaches, the Coatings Technology Handbook, Second Edition review the most recent testing methods, including infrared spectroscopy, thermal analysis, weathering, and cure monitoring...extensively details a variety of contemporary processes such as flexography, electroless plating, flame surface treatment, embossing, and calendaring ...analyses current materials and surface coatings from resins and thermoplastic elastomers to peelable medical, radiation-cured, leather, and metal coatings...and much more.

Beyond use in the consumer markets, detergents affect applications ranging from automotive lubricants to remediation techniques for oil spills and other environmental contaminants, paper and textile processing, and the formulation of paints, inks, and colorants. Faced with many challenges and choices, formulators must choose the composition of detergents carefully. The fourth and latest installment of the "Handbook of Detergents, "Part D: Formulation enables formulators to meet the demands of the increasing complexity of formulations, economic and sustainability constraints, and reducing the impact of detergents on the environment to which they will eventually be released.

The microneedle field has been expanding exponentially with innovative designs and various applications, thus capturing the interest of academic industry and regulatory sectors. Microneedles: The Future of Drug Delivery equips readers with a comprehensive understanding of microneedles; from percutaneous absorption to microneedles production, characterization, applications in drug delivery and diagnosis, to practical perspectives on the development, manufacturing, regulatory issues, and commercialization of microneedles. This book is written by a single author and thus provides complex information in a simple, elegant and cohesive style. The book is intended for graduate students, researchers, scientists and engineers working in the pharmaceutical, medical, cosmeceutical, and biotechnology industry.

This book provides readers with the most current, accurate, and practical fluid mechanics related applications that the practicing BS level engineer needs today in the chemical and related industries, in addition to a fundamental understanding of these applications based upon sound fundamental basic scientific principles. The emphasis remains on problem solving, and the new edition includes many more examples.

Overview of the development of gene therapy Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing Presents CRISPR gene therapy recent trends and applications Discusses siRNA, mRNA, and DNA plasmids

Although chemical engineering and food technology are subject areas closely related to food processing systems and food plant design, coverage of the design of food plants is often sporadic and inadequately addressed in food technology and engineering books. Some books have attempted to treat food engineering from this dual point of view but, most have not achieved balanced coverage of the two. Focusing on food processing, rather than chemical plants, Food Plant Design presents precise design details with photos and drawings of different types of food processing plants, including food processing systems, refrigeration and steam systems, conveying systems, and buildings. The authors discuss the subject in an ordered format that gives you the tools to produce food products with minimum cost. Including modeling procedures for food processing systems and auxiliary systems, they elucidate synthesis techniques and procedures. Using a clear structure for different levels of information and data on different food processing alternatives, the book outlines solutions to plant design problems in the context of overall optimization of an agro-industrial system and corresponding food chain. It provides the work procedures and techniques for solving the design problems of a food processing plant and in making a defined food product.

Discusses the modeling and analysis of nanoparticles. Covers all fundamental aspects of particle and droplet flows. Includes heat and mass transfer processes. Features new and updated sections throughout the text. Includes chapter exercises.

Demonstrates the conditions under which a 2D-LC method should be considered as an alternative to a 1D-LC method. Establishes a sound fundamental basis of the principles of the technique, followed by guidelines for method optimization. Provides a single source for technical knowledge advances and practical guidance described in recent literature. Assists with the initial decision to develop a 2D-LC method. Guides the reader in developing a high-quality method that meets the needs of their application.

*A focus on normal theory linking average power, expected power, predictive power, assurance, conditional Bayesian power and Bayesian power. *Extensions of the concepts to binomial, and time-to-event outcomes and non-inferiority trials *An investigation into the upper bound on average power, assurance and Bayesian power based on the prior probability of a positive treatment effect *Application of assurance to a series of trials in a development program and an introduction of the assurance of an individual trial conditional on the positive outcome of an earlier trial in the program, or to the successful outcome of an interim analysis *Prior distribution of power and sample size *Extension of the basic approach to proof-of-concept trials with dual success criteria *Investigation of the connection between conditional and predictive power at an interim analysis and power and assurance *Introduction of the idea of surety in sample sizing of clinical trials based on the width of the confidence intervals for the treatment effect, and an unconditional version.

Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective. Chapters are designed to cater to the needs of medicinal chemists who work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It will introduce rational drug design approaches adopted in designing chemotherapeutics and validated targets available for the purpose.

Completely revised and expanded throughout, Mixed Surfactant Systems, Second Edition surveys the latest results, newest experimental perspectives, and theoretical investigations of properties, behavior, and techniques applicable to mixed surfactant systems. This important book elucidates core theoretical notions while summarizing results of cutting-edge studies in nanoscale phase separation at monolayers of mixed amphiphiles, nanocapsule preparation through mixtures of cationic and anionic polymer amphiphiles, and the photodegradation of mixed surfactant systems by titanium dioxide. The book provides new sections on topics including: -Diffusion of mixed micelles -Mixed micelles of fluorinated and conventional surfactants -Sponge-like vesicles of mixed surfactants -Liquid crystals of mixed surfactants -Mixtures of surfactants and polymers -Photolysis of mixed surfactants Reflecting the abundance of current and emerging applications in the field, Mixed Surfactant Systems, Second Edition compiles chapters written by world-renowned leaders in industry for an up-to-date scientific account of the dynamics of mixed surfactant systems, including physicochemical properties and behavior of surfactant mixtures in detergency and surfactant precipitation.

Interconnecting the fundamentals of supercritical fluid (SCF) technologies, their current and anticipated utility in drug delivery, and process engineering advances from related methodological domains and pharmaceutical applications, this volume unlocks the potential of supercritical fluids to further the development of improved pharmaceutical products-from drug powders for respiratory delivery to drug delivery systems for controlled release.

The 29th European Symposium on Computer Aided Process Engineering, contains the papers presented at the 29th European Symposium of Computer Aided Process Engineering (ESCAPE) event held in Eindhoven, The Netherlands, from June 16-19, 2019. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students, and consultants for chemical industries.

Although nanotechnology has revolutionized fields such as medicine, genetics, biology, bioengineering, mechanics, and chemistry, its increasing application in the food industry is relatively recent in comparison. Nanotechnology is being used to discover new methods for creating new flavors, extending food shelf life, and improving food protection and nutritional value. Nanotechnology in the food industry is now being explored for intelligent nutrient delivery systems, "smart" foods, contaminant detection nanodevices and nanosensors, advanced food processing, antimicrobial chemicals, encapsulation, and green nanomaterials. This new three-volume set, Nanotechnology Horizons in Food Process Engineering, addresses a multitude of topical issues and new developments in the field. Volume 1 focuses food preservation, food packaging and sustainable agriculture, while Volume 2 looks at nanotechnology in food process engineering, applications of biomaterials in food products, and the use of modern nanotechnology for human health. The third volume explores the newest trends in nanotechnology for food applications and their application for improving food delivery systems. Together, these three volumes provide a comprehensive and in-depth look at the emerging status of nanotechnology in the food processing industry, explaining the benefits and drawbacks of various methodologies that will aid in the improvement and development of food product sourcing and food hygiene monitoring methods. Volume 2 discusses nanotechnology use in non-thermal techniques such as high-pressure processing (HPP), pulsed electric fields (PEFs), pulsed light, ultraviolet, microwave, ohmic heating, electrospinning, and nano- and microencapsulation. This volume looks at the role and application of minimal processing techniques such as ozone treatment, vacuum drying, osmotic dehydration, dense phase carbon dioxide treatment, and high-pressure assisted freezing. The successful applications of nanotechnologies on juices, meat and fish, fruits and vegetable slices, food surface, purees, milk and milk products, extraction, drying enhancement, and encapsulation of micro-macro nutrients are also considered. The volume also presents several computer-aided techniques that are emerging in the food processing sector, such as robotics, radio frequency identification (RFID), three-dimensional food printing, artificial intelligence, etc. Significant role of food properties in design of specific food and edible packaging films have been elucidated.

Handbook of Essential Oils: Science, Technology, and Applications presents the development, use and marketing of essential oils. Exciting new topics include insecticidal applications, but there is a continued focus on the chemistry, pharmacology and biological activities of essential oils. The third edition unveils new chapters including the insect repellent and insecticidal activities of essential oils, the synergistic activity with antibiotics against resistant microorganisms, essential oil applications in agriculture, plant-insect interactions, and pheromones and contaminants in essential oils. Features Presents a wide range of topics including sources, production, analysis, storage, transport, chemistry, aromatherapy, pharmacology, toxicology, metabolism, technology, biotransformation, application, utilization, and trade Includes discussions of biological activity testing, results of antimicrobial and antioxidant tests, and penetration enhancing activities useful in drug delivery Covers up-to-date regulations and legislative procedures, together with the use of essential oils in perfumes, cosmetics, feed, food, beverages, and pharmaceutical industries Unveils new chapters including the insect repellent and insecticidal activities of essential oils, the synergistic activity with antibiotics against resistant microorganisms, essential oil applications in agriculture, plant-insect interactions, and pheromones and contaminants in essential oils The American Botanical Council (ABC) named the second edition as the recipient of the 2016 ABC James A. Duke Excellence in Botanical Literature Award and recognized that essential oils are one of the fastest growing segments of the herbal product market

Advanced Polymeric Materials: Structure Property Relationships addresses the issues, characterization, durability, processing, and properties of state-of-the-art polymers. In chapters contributed by international experts-all in the vanguard of their respective specialties-it explores four distinct areas of the field that are now undergoing explosive growth: fiber reinforced composites, nanocomposites, polymer blends, and bioengineering. This welcome narrative treatment presents a unique, one-stop opportunity to discover the latest research on polymer modification from laboratories around the world.

This book, Chemistry and Industrial Techniques for Chemical Engineers, brings together innovative research, new concepts, and novel developments in the application of new tools for chemical and materials engineers. It contains significant research, reporting new methodologies, and important applications in the fields of chemical engineering as well as the latest coverage of chemical databases and the development of new methods and efficient approaches for chemists. With clear explanations, real-world examples, this volume emphasizes the concepts essential to the practice of chemical science, engineering, and technology while introducing the newest innovations in the field.